Virus infection and direct-acting antivirals in pregnancy
Clinical and Experimental Obstetrics & Gynecology, 2022 Objective: Antiviral therapy during pregnancy has always presented difficulties in clinical practice. This review covers the safety and efficacy of the direct use of antivirals during pregnancy.
Xuan Huang, Jing Tang
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Current and Future Direct-Acting Antivirals Against COVID-19 [PDF]
Frontiers in Microbiology, 2020 The coronavirus disease of 2019 (COVID-19) has caused an unprecedented global crisis. The etiological agent is a new virus called the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). As of October, 2020 there have been 45.4 million confirmed
Shiu-Wan Chan
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Planning a clinical trial programme for direct-acting antivirals for chronic viral hepatitis C [PDF]
Регуляторные исследования и экспертиза лекарственных средств, 2023 Scientific relevance. Direct-acting antivirals have significantly improved the effectiveness of treatment for hepatitis C. However, Russia and the Eurasian Economic Union lack recommendations for the clinical development of medicinal products from this ...
A. I. Gubenko +3 more
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Mechanisms of Hepatitis C Viral Resistance to Direct Acting Antivirals
Viruses, 2015 There has been a remarkable transformation in the treatment of chronic hepatitis C in recent years with the development of direct acting antiviral agents targeting virus encoded proteins important for viral replication including NS3/4A, NS5A and NS5B ...
Asma Ahmed, Daniel J. Felmlee
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Frequency of Hepatocellular Carcinoma in Cirrhotic Patients after Chronic Hepatitis C Infection Treatment with Direct-Acting Antivirals [PDF]
Afro-Egyptian Journal of Infectious and Endemic Diseases, 2022 Background and study aim: Hepatocellular carcinoma (HCC) is the 4th most common cancer in Egypt and is the 2nd leading cause of cancer-related death in both men and women. The aim of this study is to determine the frequency of HCC in cirrhotic patients
Ahmed Sharaf +3 more
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Treatment of Chronic HCV Infection with Direct Acting Antivirals
Central Asian Journal of Medical Sciences, 2021 Objectives: This study was conducted to discover the treatment outcome and side effects of chronic hepatitis C virus patients treated with Direct-Acting Antivirals (DAAs).
Bekhbold Dashtseren +12 more
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The Egyptian Journal of Internal Medicine, 2022 Background Direct-acting antivirals (DAAs) have revolutionized the therapy of HCV infection with higher sustained virological response (SVR) rates. Fibrosis regression after achieving SVR to DAA remains to be evaluated in chronic hepatitis C patients ...
Ramy H. Agwa +5 more
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Effect of Direct-Acting Antivirals on Lipid and Glucose Metabolism in Chronic HCV Patients [PDF]
Minia Journal of Medical Research, 2019 Introduction: Hepatitis C virus (HCV) infection is a global public health burden, total global HCV prevalence is estimated at 2.5% (177 million of HCV infected adults), Considerable differences are present among different populations.
Mohammed Mohammed +2 more
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Barriers to treatment of failed or interferon ineligible patients in the era of DAA: single center study [PDF]
Clinical and Molecular Hepatology, 2017 Background/Aims Interferon-based treatment is not appropriate for a large number of patients with chronic hepatitis C for various medical and social reasons.
Kwang Il Seo +5 more
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Lipid response in Hcv patients treated by direct acting antivirals [PDF]
Minia Journal of Medical Research, 2020 Background: sustained virological response (SVR) can be achived in high percentage of HCV patients with the availability of direct acting antiviral agents DAAs.
Asmaa Mohammed +3 more
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