Results 11 to 20 of about 16,194 (165)
Effect of Direct-Acting Antivirals on Lipid and Glucose Metabolism in Chronic HCV Patients [PDF]
Minia Journal of Medical Research, 2019 Introduction: Hepatitis C virus (HCV) infection is a global public health burden, total global HCV prevalence is estimated at 2.5% (177 million of HCV infected adults), Considerable differences are present among different populations.
Mohammed Mohammed +2 more
doaj +1 more source
Barriers to treatment of failed or interferon ineligible patients in the era of DAA: single center study [PDF]
Clinical and Molecular Hepatology, 2017 Background/Aims Interferon-based treatment is not appropriate for a large number of patients with chronic hepatitis C for various medical and social reasons.
Kwang Il Seo +5 more
doaj +1 more source
Lipid response in Hcv patients treated by direct acting antivirals [PDF]
Minia Journal of Medical Research, 2020 Background: sustained virological response (SVR) can be achived in high percentage of HCV patients with the availability of direct acting antiviral agents DAAs.
Asmaa Mohammed +3 more
doaj +1 more source
Acta Scientiarum. Health Sciences, 2023 To report the sociodemographic and clinical profile of patients treated with direct-action antivirals (DAAs). Patients infected with hepatitis C virus in current treatment were followed up in a pharmaceutical office.
Karem Aline Pegoraro +3 more
doaj +1 more source
Direct-acting antivirals for chronic hepatitis C [PDF]
Cochrane Database of Systematic Reviews, 2016 Millions of people worldwide suffer from hepatitis C, which can lead to severe liver disease, liver cancer, and death. Direct-acting antivirals (DAAs) are relatively new and expensive interventions for chronic hepatitis C, and preliminary results suggest that DAAs may eradicate hepatitis C virus (HCV) from the blood (sustained virological response ...
Jakobsen, Janus C. +15 more
openaire +8 more sources
Therapeutic Advances Against ZIKV: A Quick Response, a Long Way to Go
Pharmaceuticals, 2019 Zika virus (ZIKV) is a mosquito-borne flavivirus that spread throughout the American continent in 2015 causing considerable worldwide social and health alarm due to its association with ocular lesions and microcephaly in newborns, and Guillain−Barr&
Juan-Carlos Saiz
doaj +1 more source
The occurrence of thrombotic thrombocytopenic purpura during treatment of HCV with direct-acting antiviral agents [PDF]
African Journal of Gastroenterology and Hepatology, 2018 Background and aim Experts have reported thrombocytopenia is linked to chronic liver disease in up to 70% of patients with advanced fibrosis and portal hypertension. The occurrence of thrombotic thrombocytopenic purpura (TTP) with HCV infection is a rare
Amr Hanafy, Waseem Seleem, Salem Mohamed
doaj +1 more source
SHARED: An International Collaboration to Unravel Hepatitis C Resistance
Viruses, 2021 The advent of direct-acting antivirals (DAAs) has transformed the treatment landscape of hepatitis C [...]
Anita Y.M. Howe +12 more
doaj +1 more source
New horizons in hepatitis C antiviral therapy with direct-acting antivirals [PDF]
Hepatology, 2013 Abstract Most direct-acting antivirals (DAAs) that are being developed as therapy against hepatitis C virus target the NS3/4A protease, the NS5A protein, and the NS5B polymerase. The latter enzyme offers different target sites: the catalytic domain for nucleos(t)ide analogues as well as a number of allosteric sites ...
Alessio, Aghemo, Raffaele, De Francesco
openaire +2 more sources
Frontiers in Microbiology, 2023 This article systematically presents the current clinically significant therapeutic developments for the treatment of COVID-19 by providing an in-depth review of molecular mechanisms of action for SARS-CoV-2 antivirals and critically analyzing the ...
Oana Săndulescu +8 more
doaj +1 more source