Results 41 to 50 of about 48,056 (216)

Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria

Nature Communications, 2022
Cryo-EM reveals an asymmetric bacterial photosynthetic supercomplex built upon a homodimeric reaction center core. The structure provides mechanistic insights into light excitation transfer and a possible evolutionary transition intermediate of ...
Ryan Puskar, Chloe Du Truong, Kyle Swain, Saborni Chowdhury, Ka-Yi Chan, Shan Li, Kai-Wen Cheng, Ting Yu Wang, Yu-Ping Poh, Yuval Mazor, Haijun Liu, Tsui-Fen Chou, Brent L. Nannenga, Po-Lin Chiu   +13 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Experimental fission study using multi-nucleon transfer reactions

EPJ Web of Conferences, 2017
It is shown that the multi-nucleon transfer reactions is a powerful tool to study fission of exotic neutron-rich actinide nuclei, which cannot be accessed by particle-capture or heavy-ion fusion reactions. In this work, multi-nucleon transfer channels of
Nishio Katsuhisa, Hirose Kentaro, Léguillon Romain, Makii Hiroyuki, Orlandi Riccardo, Tsukada Kazuaki, Smallcombe James, Chiba Satoshi, Aritomo Yoshihiro, Tanaka Shouya, Ohtsuki Tsutomu, Tsekhanovich Igor, Petrache Costel M., Andreyev Andrei   +13 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

High Sensitivity Strain Sensors Using Four-Core Fibers through a Corner-Core Excitation

Micromachines, 2022
A weakly-coupled multicore fiber can generate supermodes when the multi-cores are closer to enter the evanescent power coupling region. The high sensitivity strain sensors using tapered four-core fibers (FCFs) were demonstrated.
Lina Suo, Ya-Pei Peng, Cheng-Kai Yao, Shijie Ren, Xinhe Lu, Nan-Kuang Chen   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Investigation of excitation energy dependence of fission modes in actinides through transfer-induced fission [PDF]

EPJ Web of Conferences
Nuclear fission outcomes are strongly driven by different shell-stabilized fission modes. The resulting fission fragment properties sensitively depend on the excitation energy and the fissioning nuclide.
Lee H., Cook K. J., Buete J., Hinde D. J., Dasgupta M., Bezzina L. T., Hayles S. L., Lakelin M. K., Seabra C. C., Tran T., Webber M. M.   +10 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source