Results 101 to 110 of about 1,107,456 (300)

Experimental tests on the lifetime Asymmetry

, 2011
The experimental test problem of the left-right polarization-dependent lifetime asymmetry is discussed. It shows that the existing experiments cannot demonstrate the lifetime asymmetry to be right or wrong after analyzing the measurements on the neutron,
Abreu P., Amsler C., GUANG-JIONG NI, Kennedy D. C., Shi Z. Q., Shi Z. Q., ZHI-QIANG SHI   +6 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Standard Model Top Quark Asymmetry at the Fermilab Tevatron

, 2006
Top quark pair production at proton-antiproton colliders is known to exhibit a forward-backward asymmetry due to higher-order QCD effects. We explore how this asymmetry might be studied at the Fermilab Tevatron, including how the asymmetry depends on the
D. Rainwater, F. A. Berends, L. Lyons, M. T. Bowen, P. Nason, S. D. Ellis   +5 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

EEG-based major depressive disorder recognition by neural oscillation and asymmetry

Frontiers in Neuroscience
BackgroundMajor Depressive Disorder (MDD) is a pervasive mental health issue with significant diagnostic challenges. Electroencephalography (EEG) offers a non-invasive window into the neural dynamics associated with MDD, yet the diagnostic efficacy is ...
Xinyu Liu, Xinyu Liu, Haoran Zhang, Haoran Zhang, Yi Cui, Tong Zhao, Bin Wang, Bin Wang, Xiaomeng Xie, Xiaomeng Xie, Sixiang Liang, Sixiang Liang, Sha Sha, Sha Sha, Yuxiang Yan, Xixi Zhao, Xixi Zhao, Ling Zhang, Ling Zhang   +18 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

CP violation in scatterings, three body processes and the Boltzmann equations for leptogenesis

, 2007
We obtain the Boltzmann equations for leptogenesis including decay and scattering processes with two and three body initial or final states. We present an explicit computation of the CP violating scattering asymmetries.
A. Abada, A. Abada ., A. De Simone, A. Strumia, A.D. Sakharov, E. Nardi, E. Nardi, Enrico Nardi, Esteban Roulet, F.X. Josse-Michaux, G. Engelhard, Juan Racker, M.-C. Chen, P. Ramond, S. Davidson, T. Shindou, T. Yanagida, W. Buchmuller, W. Buchmuller, Y. Nir   +19 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source