Results 81 to 90 of about 1,107,456 (300)

Visual Representation Determines Search Difficulty: Explaining Visual Search Asymmetries

open access: yesFrontiers in Computational Neuroscience, 2011
In visual search experiments there exist a variety of experimental paradigms in which a symmetric set of experimental conditions yields asymmetric corresponding task performance.
Neil eBruce, John eTsotsos
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transverse Spin Asymmetries in Drell-Yan Processes: $\mathbf p^{\uparrow} p \to \mu^+ \mu^- X$}

open access: yes, 2001
We consider two different spin asymmetries in Drell-Yan processes generated by the collisions of an unpolarized proton beam on transversely polarized protons: the muon helicity asymmetry and the left-right asymmetry.
Di Salvo, Elvio
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The CP-violating asymmetry in K_L -> pi+ pi- e+ e-

open access: yes, 2001
We update the theoretical analysis of the CP-violating asymmetry in the decay K_L -> pi+ pi- e+ e-, relying on chiral perturbation theory and on the most recent phenomenological information.
Alavi-Harati   +32 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Asymmetry to symmetry transition of Fano line-shape: Analytical derivation

open access: yes, 2012
An analytical derivation of Fano line-shape asymmetry ratio has been presented here for a general case. It is shown that Fano line-shape becomes less asymmetric as \q is increased and finally becomes completely symmetric in the limiting condition of q ...
B Parida   +32 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Anisotropic imprint of long-wavelength tensor perturbations on cosmic structure

open access: yes, 2013
Inflationary models predict a correlation between primordial density perturbations (scalar metric perturbations) and gravitational waves (tensor metric perturbations) in the form of a scalar-scalar-tensor three-point correlation, or bispectrum in Fourier
Dai, Liang   +2 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

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