Results 61 to 70 of about 507,656 (295)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A parietal biomarker for ADHD liability:As predicted by The Distributed Effects Perspective Model of ADHD

open access: yesFrontiers in Psychiatry, 2015
Background: We previously hypothesized that poor task-directed sensory information processing should be indexed by increased weighting of right hemisphere (RH) biased attention and visuo-perceptual brain functions during task operations, and have ...
T. Sigi eHale   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Chiral Neuronal Motility: The Missing Link between Molecular Chirality and Brain Asymmetry

open access: yes, 2019
Left–right brain asymmetry is a fundamental property observed across phyla from invertebrates to humans, but the mechanisms underlying its formation are still largely unknown.
Atsushi Tamada
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Psychosocial aspects of domestic violence

open access: yesRicerca Psicoanalitica, 2020
The work carried out and the experiences of the clinicians show that the phenomenon of domestic violence is much more evident than what is believed in "normal" family and social contexts.
Ana Luisa Botto
doaj   +1 more source

Model development for the analysis of reducing voltage asymmetry methods in power supply systems

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2022
THE PURPOSE. To consider the issues of ensuring the quality of electricity in power supply systems. Show that the quality of electrical energy during the operation of power supply systems in certain cases may be violated, including due to uneven loading ...
V. I. Biryulin, D. V. Kudelina
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells

open access: yesNature Communications, 2016
The molecular mechanisms determining the temporal identity patterns of self-renewing progenitors during cerebral development are largely unclear. Here, using single cell transcriptome analyses, the authors find progenitor temporal identity arises ...
Mayumi Okamoto   +7 more
doaj   +1 more source

Lessons from the Discovery of Mitochondrial Fragmentation (Fission): A Review and Update

open access: yesCells, 2019
Thirty-five years ago, we described fragmentation of the mitochondrial population in a living cell into small vesicles (mitochondrial fission). Subsequently, this phenomenon has become an object of general interest due to its involvement in the process ...
Dmitry B. Zorov   +9 more
doaj   +1 more source

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