Results 71 to 80 of about 1,107,456 (300)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Scale-dependent hemispherical asymmetry from general initial state during inflation

open access: yes, 2014
We consider a general initial state for inflation as the mechanism for generating scale-dependent hemispherical asymmetry. An observable scale-dependent non-Gaussianity is generated that leads to observable hemispherical asymmetry from the super-horizon ...
Firouzjahi, Hassan   +2 more
core   +1 more source

Isospin dependence of nuclear matter symmetry energy coefficients [PDF]

open access: yes, 2001
Generalized symmetry energy coefficients of asymmetric nuclear matter are obtained as screening functions. The dependence of the isospin symmetry energy coefficient on the neutron proton (n-p) asymmetry may be determined unless by a constant (exponent ...
Aboussir   +40 more
core   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

CP violation in charged Higgs decays in the MSSM

open access: yes, 2006
In the MSSM with complex parameters loop corrections to the decays $H^+ \to t \bar{b}$ and $H^- \to \bar{t} b$ with $t \to b W$ and $W \to l \nu$ lead to CP-violating asymmetries: a decay rate asymmetry, a forward-backward asymmetry and an energy ...
A. Belyaev   +11 more
core   +1 more source

Baryon asymmetry and mass matrices [PDF]

open access: yes, 2001
In the framework of the baryogenesis via leptogenesis mechanism we study the link between the amount of baryon asymmetry and neutrino mass matrices. In particular, neglecting phases, we find that if the Dirac neutrino mass matrix is related to the up ...
Falcone, D.
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Origins of the di-jet asymmetry in heavy ion collisions

open access: yes, 2015
The di-jet asymmetry --- the measure of the momentum imbalance in a di-jet system --- is a key jet quenching observable. Using the event generator \jewel we show that the di-jet asymmetry is dominated by fluctuations both in proton-proton and in heavy ...
Milhano, José Guilherme   +1 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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