Seasonal Variations for Newly Prescribed Urate-Lowering Drugs for Asymptomatic Hyperuricemia and Gout in Japan [PDF]
Frontiers in PharmacologyBackground: Urate-lowering drugs (ULDs) have been approved for treatment of asymptomatic hyperuricemia and gout in Japan. Although serum urate levels and rates of gout onset are known to have seasonal variations, no survey results regarding the ...
Tomoaki Morioka +2 more
exaly +4 more sources
Ultrasonographic Evaluation of Femoral Cartilage Thickness in Participants with Asymptomatic Hyperuricemia: A Case-Control Study [PDF]
Acta Clinica Croatica, 2023 The aim was to evaluate the effect, if any, of asymptomatic hyperuricemia on distal femoral cartilage thickness through musculoskeletal ultrasonography.
İlker Fatih Sari +4 more
doaj +2 more sources
Prevalence of Asymptomatic Hyperuricemia and Associated Factors in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Southern Vietnam [PDF]
DiagnosticsBackground/Objectives: Asymptomatic hyperuricemia is a common yet frequently overlooked condition in the management of patients with type 2 diabetes mellitus (T2DM), despite its potential association with cardiovascular events.
Kim Son Tran +2 more
doaj +2 more sources
Association between normal-weight central obesity and asymptomatic hyperuricemia in Korean adults: a cross-sectional study [PDF]
BMC Public HealthBackground Obesity increases the risk of hyperuricemia. Recent studies have shown that normal-weight central obesity increases the risk of cardiometabolic disease.
Minok Shim +4 more
doaj +2 more sources
Asymptomatic Hyperuricemia Is Associated with Achilles Tendon Rupture through Disrupting the Normal Functions of Tendon Stem/Progenitor Cells [PDF]
Stem Cells International, 2022 Hyperuricemia is a metabolic disorder that is essential to the development of inflammatory gout, with increasing prevalence over recent years. Emerging clinical findings has evidenced remarkable tendon damage in individuals with longstanding asymptomatic
Jingjing Liang +12 more
doaj +2 more sources
Plasma and Urinary Metabolomic Analysis of Gout and Asymptomatic Hyperuricemia and Profiling of Potential Biomarkers: A Pilot Study [PDF]
BiomedicinesGout results from monosodium urate deposition caused by hyperuricemia, but most individuals with hyperuricemia remain asymptomatic. The pathogenesis of gout remains uncertain.
Yuki Ohashi +5 more
doaj +2 more sources
Hyperuricemic persons use more analgesics than normouricemic—is asymptomatic hyperuricemia really asymptomatic? [PDF]
BMC MedicineBackground Gout is a crystal deposition disorder that leads to painful joint inflammation. Its mandatory precursor—hyperuricemia—may be associated with musculoskeletal pain even in the absence of gout attacks.
Janis Timsans +7 more
doaj +2 more sources
Association between asymptomatic hyperuricemia and kidney stones [PDF]
PLoS ONEBackgroundNephrolithiasis is commonly observed in patients with gout; however, the role of asymptomatic hyperuricemia in stone formation remains unclear.
Jun Ho Lee +4 more
doaj +3 more sources
Frontiers in Pharmacology, 2021 Objective: The study aimed to thoroughly address the influence of benzbromarone and allopurinol on the risk of the development of type 2 diabetes mellitus (T2DM) in people with asymptomatic hyperuricemia.Methods: We conducted a retrospective cohort study
Cheng-Li Lin +2 more
exaly +3 more sources
Effects of uric acid-lowering therapy (ULT) on renal outcomes in CKD patients with asymptomatic hyperuricemia: a systematic review and meta-analysis [PDF]
BMC NephrologyBackground It is well known that asymptomatic hyperuricemia and gout play an important role in patients with chronic kidney disease (CKD). However, the effect of uric acid-lowering therapy (ULT) on the prognosis of CKD patients with asymptomatic ...
Yuxin Luo +9 more
doaj +2 more sources