Results 71 to 80 of about 233,212 (284)

Preliminary Test Estimation for Parallel 2-Sampling in Autoregressive Model

Stats
The purpose of this paper is to discuss the problem of estimation and testing the equality of two autoregressive parameters of two first-order autoregressive processes AR(1), where for each process, the observations are made at different time points. The
Syed Ejaz Ahmed, Arsalane Chouaib Guidoum, Sara Bendjeddou   +2 more
doaj   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Hybrid Monte Carlo simulation with Fourier acceleration of the N = 2 principal chiral model in two dimensions

Physics Letters B
Motivated by the similarity to QCD, specifically the property of asymptotic freedom, we simulate the dynamics of the SU(2) × SU(2) model in two dimensions using the Hybrid Monte Carlo algorithm.
Roger Horsley, Brian Pendleton, Julian Wack   +2 more
doaj   +1 more source

A Numerical Comparison for a Discrete HIV Infection of CD4+ T-Cell Model Derived from Nonstandard Numerical Scheme

Journal of Applied Mathematics, 2013
A nonstandard numerical scheme has been constructed and analyzed for a mathematical model that describes HIV infection of CD4+ T cells. This new discrete system has the same stability properties as the continuous model and, particularly, it preserves the
Mevlüde Yakıt Ongun, İlkem Turhan
doaj   +1 more source

An Alternative Sense of Asymptotic Efficiency [PDF]

The paper studies the asymptotic efficiency and robustness of hypothesis tests when models of interest are defined in terms of a weak convergence property.
Mueller, Ulrich
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Asymptotic Comparison of Parameters Estimates of Two-parameter Weibull Distribution

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2019
The Weibull distribution is frequently applied in various fields, ranging from economy, business, biology, to engineering. This paper aims at estimating the parameters of two-parameter Weibull distribution are determined.
Tereza Konečná, Zuzana Hübnerová
doaj   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Spatiotemporal averaging resolution of high importance within Earth-observation-based light use efficiency models of gross primary production

Science of Remote Sensing
Gross primary production (GPP) of the vegetation is the largest carbon exchange process of the global carbon cycle. Currently, within satellite-based remote sensing, GPP is generally modelled using linear light use efficiency models where GPP is related ...
Torbern Tagesson, Paul Senty, Ousmane Diatta, Zhanzhang Cai, Aleksander Wieckowski, Ousmane Ndiaye, Jonas Ardö   +6 more
doaj   +1 more source

Optimal Grazing Exclusion Duration to Enhance Soil Carbon Sequestration in Degraded Grasslands

Advanced Science, EarlyView.
Across China, grazing exclusion reaches the national mean soil organic carbon recovery benchmark sooner in high‐MAP regions (> 500 mm), but recovery is much slower where MAP < 300 mm. Scaling this strategy to 70% of China's degraded grasslands would sequester about 1.52 Pg of soil carbon over 10 years—roughly 17% of annual global fossil‐fuel emissions.
Bin Zhang, Chongzhi Sun, Dongmei Xue, Paul Christiaan Struik, Tongrui Zhang, Jiayue Liu, Tingting Xing, Ziyang Liu, Shiming Tang, Ke Jin   +9 more
wiley   +1 more source