Results 191 to 200 of about 166,779,119 (261)

Free Fatty Acids Carried by Lipoproteins: Revisiting the Overlooked Cargo

open access: yesActa Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT Free fatty acids (FFAs) are hydrophobic and therefore cannot enter the bloodstream at appreciable levels unless they are solubilized by FFA carriers. Albumin has been appreciated for years as the major FFA carrier, but it is not the only carrier.
Gregory C. Henderson   +2 more
wiley   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

open access: yesClinical Endocrinology, Volume 105, Issue 3, Page 271-284, September 2026.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu   +5 more
wiley   +1 more source

Dual Glucagon and GLP‐1 Receptor Agonist Survodutide Improves Biomarkers of Beta‐Cell Function and Insulin Sensitivity in People With Type 2 Diabetes or Living With Overweight/Obesity

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8242-8253, September 2026.
ABSTRACT Aims This post hoc analysis evaluated the effect of survodutide on beta‐cell function, insulin sensitivity, and glucose biomarkers in two phase 2 trial populations. Materials and Methods Trial 1404‐0002 randomised 413 participants with type 2 diabetes on metformin to receive survodutide, placebo, or semaglutide over 16 weeks.
Elif I. Ekinci   +5 more
wiley   +1 more source

Cardiovascular Diseases and All‐Cause Mortality Risk in Patients With Prehypertension and Noncommunicable Diseases: Results From the Kailuan Study

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 9, September 2026.
ABSTRACT It remains unclear whether prehypertension combined with noncommunicable diseases (NCDs) is associate with higher risks of cardiovascular diseases (CVD) and all‐cause mortality. The study aimed to investigate the associations of prehypertension with CVD and all‐cause mortality in individuals with or without NCDs.
Ruiying Zhang   +7 more
wiley   +1 more source

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

open access: yesJournal of Internal Medicine, Volume 300, Issue 3, Page 312-328, September 2026.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca   +16 more
wiley   +1 more source

The relationship between atherogenic index of plasma and erectile dysfunction: a cross-sectional observational study. [PDF]

open access: yesWorld J Urol
Turkoglu AR   +9 more
europepmc   +1 more source

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