Results 181 to 190 of about 166,779,119 (261)

Calpeptin Reduces Extracellular Vesicle Secretion and Induces Anti‐Inflammatory Effects but Upregulates HO‐1 and Alters Adiponectin Levels in Human Adipocytes

open access: yesJournal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Recent studies have shown that adipose tissue (AT) secretes elevated levels of extracellular vesicles (EVs) in obesity, and these EVs play roles in metabolic diseases. The inhibition of calpains has anti‐inflammatory and anti‐fibrotic effects on AT in mice and reduces EV secretion in some cell types in vitro.
Johanna Matilainen   +18 more
wiley   +1 more source

Triglyceride‐Related Indices and Risk of Acute Pancreatitis: A Prospective Study in UK Biobank

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
ABSTRACT Triglyceride‐related indices, including triglyceride‐glucose (TyG), TyG related to body mass index (TyG‐BMI), TyG related to waist circumference (TyG‐WC), TyG related to waist‐to‐height ratio (TyG‐WHtR), atherogenic index of plasma (AIP), cardiometabolic index (CMI), visceral adiposity index (VAI), and lipid accumulation product (LAP), are ...
Jing‐Bo Li   +3 more
wiley   +1 more source

Type 2 Diabetes Mellitus Modifies the Prognostic Value of LDL Particle Size in Statin‐treated Patients With Coronary Artery Disease: A Large‐scale Cohort Study

open access: yesMedComm, Volume 7, Issue 9, September 2026.
The LDL‐C/ApoB ratio, a marker of LDL size, showed significant prognostic value in statin‐treated CAD patients depending on diabetes status. A higher ratio was linked to lower cardiovascular risk only in patients with type 2 diabetes, suggesting it may be a superior biomarker for risk stratification beyond conventional lipids in this high‐risk group ...
Xiaohui Bian   +6 more
wiley   +1 more source

Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi   +6 more
wiley   +1 more source

Integrating Conventional and Emerging Approaches in Cardiovascular Risk Assessment and Management

open access: yesPublic Health Challenges, Volume 5, Issue 3, September 2026.
Conventional risk factors (hypertension, dyslipidaemia, diabetes, smoking, obesity and physical inactivity) account for roughly 70% of population‐attributable cardiovascular risk and anchor a proposed three‐tier pathway: universal low‐cost assessment (Tier 1), selective testing such as hsCRP or PRS where it would change management (Tier 2) and resource‐
Sana Rasheed   +4 more
wiley   +1 more source

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