Results 161 to 170 of about 166,779,119 (261)

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Upcoming therapies for steatotic liver disease: Translating breakthroughs into clinical practice

Journal of Internal Medicine, Volume 300, Issue 4, Page 440-460, October 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and a leading cause of cirrhosis, hepatocellular carcinoma, and cardiometabolic morbidity. Often clinically silent until advanced fibrosis develops, management has largely relied on lifestyle interventions, with limited ...
Philip N. Newsome, Saima Ajaz
wiley   +1 more source

Comparison of plasma atherogenic index in patients with and without coronary artery ectasia

ÖZET Koroner Ektazisi Olan Hastalarda Plazma Aterojenik İndeksinin Ektazisi Olmayan Hastalarla Karşılaştırılması Dr. Sezer Markirt, Uzmanlık Tezi, ADIYAMAN, 2024 Amaç: Bu tezin amacı, plazma trigliseridlerinin (TG) yüksek yoğunluklu lipoprotein ...
Markirt, Sezer
core  

Short Sleep Duration Is Positively Associated With Traditional and Non‐Traditional Markers of Adiposity and Cardiometabolic Risk in Individuals at Secondary Healthcare: A Cross‐Sectional Study

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
This cross‐sectional study involving 937 adults at high cardiovascular risk found a positive association between short sleep duration (< 7 h/night) and traditional and non‐traditional markers of adiposity (abdominal obesity, overweight, and high visceral adiposity index [VAI]), a non‐traditional marker of glucose metabolism disruption (high ...
Nathallia Maria Cotta e Oliveira, Mariana De Santis Filgueiras, Gilmara Alves Zanirate, Flávia Galvão Cândido, Sarah Aparecida Vieira Ribeiro, Helen Hermana Miranda Hermsdorff   +5 more
wiley   +1 more source

Mechanistic Insights Into the Association Between Gut Microbiota Diversity and Atherosclerosis, Acute Coronary Syndrome, and Peripheral Arterial Disease Progression

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy, Usamah Sayed, Zarina Nasirova, Quvonch Tursunov, Omer Qutaiba B. Allela, Lara Asim Kzar, Rajashree Panigrahi, Neeraj Bainsal   +7 more
wiley   +1 more source

Effects of Zinc Supplementation on Glycemic Control, Insulin Resistance, Inflammation and Oxidative Stress in Diabetes: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Zinc supplementation in diabetes is associated with improved insulin sensitivity, lipid profile, antioxidant status and reduced inflammation, without significant effects on glycemic indices. Overall, evidence from randomized trials supports zinc as a beneficial metabolic adjunct with moderate‐to‐high certainty. ABSTRACT Objectives Diabetes mellitus (DM)
Jessica Paola Loaiza‐Giraldo, Florencia Amigo‐Fierro, Camila Ignacia Cancino‐Castro, Matias Donoso‐Emig, Murtaja Satea, Ignacia Farías‐Quinteros, Alejandro Bruna‐Mejias, Pablo Nova‐Baeza, Mathias Orellana‐Donoso, Héctor Gutiérrez‐Espinoza, Gloria Cifuentes‐Suazo, Juan Sanchis‐Gimeno, Maria Piagkou, Vitor E. Valenti, Jose E. Leon‐Rojas, Juan José Valenzuela‐Fuenzalida   +15 more
wiley   +1 more source

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed, Abdinasir Adam Shidane, Abdullahi Mohamud Abdiasis, Mohamed Hassan Hussein, Ayaanle Osman Ibrahim, Anas Ali Abdi, Kowthar Ismail Hashi, Mohamed Abdullahi Mohamud, Ali Jimale Mohamed   +8 more
wiley   +1 more source

Potential Involvement of Redox and Inflammatory Signalling in the Antihyperglycemic and Antioxidant Effects of Harmaline in Male Mice With Type 2 Diabetes

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
HAR may improve T2DM by enhancing antioxidant defences through Nrf2 activation while suppressing inflammation and RAS activity, supporting its capability to treat diabetes. ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation.
Farima Malekinia, Akram Ahangarpour, Khojasteh Hoseinynejad, Seyyed Ali Mard, Maryam Radan, Fereshteh Nejaddehbashi   +5 more
wiley   +1 more source

The Shared IL‐12/IL‐35 p35 Subunit Is Associated With Heightened Atherogenic Risk in African Patients With Type 2 Diabetes

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Hyperglycaemia‐driven metabolic dysfunction is associated with elevated circulating levels of the shared IL‐12/IL‐35 p35 subunit and an adverse atherogenic phenotype. These findings identify p35 as a promising biomarker of cardiovascular risk in patients with type 2 diabetes.
Tawanda M. Nyambuya, Edwig Shingenge, Fransina Ndevahoma, Bongani B. Nkambule   +3 more
wiley   +1 more source

Association between the Atherogenic Index of Plasma and in-Hospital Mortality in Individuals with Sepsis. [PDF]

Yonsei Med J
Li P, Zhu X, Zheng W, Zhang L, Liu L.
europepmc   +1 more source