Results 81 to 90 of about 42,051 (254)

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Weight loss surgery in adolescents corrects high-density lipoprotein subspecies and their function. [PDF]

, 2017
Background/objectiveYouth with obesity have an altered high-density lipoprotein (HDL) subspecies profile characterized by depletion of large apoE-rich HDL particles and an enrichment of small HDL particles.
Davidson, WS, Elder, D, Heink, A, Hui, DY, Inge, TH, Kelesidis, T, Melchior, JT, Sexmith, H, Shah, AS   +8 more
core   +1 more source

Lipid Profile Alterations Across Coronary Heart Disease, Metabolic Syndrome, and Nephrotic Syndrome

Journal of Clinical Laboratory Analysis, EarlyView.
CHD, MetS, and NS exhibit distinct dyslipidemia patterns. TC, TG, ApoB, ApoE, and sdLDL‐C are key markers for disease differentiation. This study found that elevated TC and sdLDL‐C were key pathogenic factors in CHD. In contrast, TG and ApoB played significant roles in the pathogenesis of MetS.
Shudong Tan, Tianji Qu, Jing Ai, Yaoyang Fu   +3 more
wiley   +1 more source

Anti-atherogenic potential of jujube, saffron and barberry: anti-diabetic and antioxidant actions [PDF]

, 2015
Atherogenic dyslipidemia, characterized by an increased level of lipoprotein (a) and a decreased level of adiponectin, is a major risk factor for cardiovascular diseases in diabetic patients.
Asghari, Somaye, Hemmati, Mina, Karamian, Mehdi, Mehrpour, Omid, Nasouti, Roya, Zarban, Asghar, Zohoori, Elham   +6 more
core   +1 more source

Cardioprotective effect of spirulina on cafeteria diet‐induced cardiac injury in silico and in vivo study

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Obesity is a major risk factor for cardiovascular disease, primarily due to its effects on lipid metabolism, oxidative stress, and inflammation. The aim of this study was to evaluate the effects of spirulina (SP) on cafeteria diet (CD)‐induced myocardial oxidative stress and inflammation using biochemical, histological, and in ...
Fatma Arrari, Mohamed‐Amine Jabri, Imen Hammami, Hichem Sebai   +3 more
wiley   +1 more source

Relationship between dietary intake and atherogenic index of plasma in cardiometabolic phenotypes: a cross-sectional study from the Azar cohort population

Journal of Health, Population and Nutrition
Background Cardiovascular diseases are a leading cause of global mortality, with diet playing a key role in their progression. The Atherogenic Index of Plasma (AIP) is a predictive marker for cardiovascular risk, but its association with dietary intake ...
Shirin Soheilifard, Elnaz Faramarzi, Reza Mahdavi   +2 more
doaj   +1 more source

Association between the plasma atherogenic index and type 2 diabetes in Chinese population: prospective cohort study based on 4C study

Frontiers in Endocrinology
BackgroundCurrently, the plasma atherogenic index (AIP) is mainly used to predict atherosclerosis and cardiovascular diseases. Therefore, we aim to investigate the potential association between AIP and type 2 diabetes through a prospective cohort study ...
Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Rui Cao, Rui Cao, Rui Cao, Rui Cao, Rui Cao, Qin Wan, Qin Wan, Qin Wan, Qin Wan, Qin Wan   +14 more
doaj   +1 more source

Triglyceride‐Related Indices and Risk of Acute Pancreatitis: A Prospective Study in UK Biobank

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triglyceride‐related indices, including triglyceride‐glucose (TyG), TyG related to body mass index (TyG‐BMI), TyG related to waist circumference (TyG‐WC), TyG related to waist‐to‐height ratio (TyG‐WHtR), atherogenic index of plasma (AIP), cardiometabolic index (CMI), visceral adiposity index (VAI), and lipid accumulation product (LAP), are ...
Jing‐Bo Li, Yu‐Jiao Zhu, Yang‐Jie Liao, Jia‐Yi Wang   +3 more
wiley   +1 more source

Triacylglycerol‐Based Insulin Resistance Indices and Post‐Transplantation Diabetes Mellitus After Liver Transplantation

Lipids, EarlyView.
ABSTRACT Background: Post‐transplant diabetes mellitus (PTDM) is a common complication following liver transplant (LT) and is associated with adverse outcomes. The triacylglycerol‐glucose product (TyG) and the triacylglycerol‐to‐high‐density lipoprotein (HDL) cholesterol ratio (TAG/HDL‐c) are indices that can serve as triacylglycerol‐based proxies for ...
Mateo Chvatal‐Medina, Yakun Li, Adrian Post, Margery A. Connelly, Han Moshage, Stephan J. L. Bakker, Vincent E. de Meijer, Hans Blokzijl, Robin P. F. Dullaart, on behalf of TransplantLines investigators   +9 more
wiley   +1 more source

Endothelial dysfunction in adolescents and young adults with nonalcoholic liver disease [PDF]

, 2019
Nonalcoholic liver disease is a global public health problem that increases cardiovascular morbidity and mortality in these patients. This paper discusses endothelial dysfunction among patients (adolescents and young adults) with nonalcoholic liver ...
Donoiu, Ionuț, Istrătoaie, Octavian, Moise, Cristiana G, Mustafa, Edme R, Rogoveanu, Ion, Tudorașcu, Diana R, TÂRTEA, Georgică C   +6 more
core   +1 more source