Results 101 to 110 of about 706,977 (192)
The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding
Journal of Lipid Research, 2009 Lectin-like oxidized LDL (ox-LDL) receptor-1 (LOX-1) is a type-II transmembrane protein that belongs to the C-type lectin family of molecules. LOX-1 acts as a cell surface endocytosis receptor and mediates the recognition and internalization of ox-LDL by
Omar L. Francone +10 more
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The Lancet, 1969 The idea that excessive concentrations of insulin might contribute to the development of atherosclerosis appeared in the mid 1960s and the evidence was first reviewed in a paper published in 1969 [1]. Since then, data, both clinical and experimental, has continued to accumulate, most of it supportive of the hypothesis, although some of the details have
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Circulation, 1968 The effectiveness of the research endeavor in atherogenesis is searchingly considered because neither how to prevent nor how to cure atherosclerosis is known, and there is no decision about what atherosclerosis looks like. In the overview one of the most serious problems is failure to see the whole problem. Systematic marshalling of detail is
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Alterations of the plasma lipoproteins and apoproteins following cholesterol feeding in the rat
Journal of Lipid Research, 1977 The feeding of cholesterol to rats resulted in marked alterations in the type and distribution of the plasma lipoproteins and their apoproteins. The hyperlipoproteinemia was characterized by an increase in the d < 1.006 lipoproteins (B-VLDL and VLDL), an
R W Mahley, K S Holcombe
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Childhood Obesity and Familial Hypercholesterolemia: Genetic Diseases that Contribute to Cardiovascular Disease [PDF]
, 2014 Childhood obesity occurs as the result of an imbalance between caloric intake and energy expenditure. Genetic risk factors for obesity have become an area of research due to its permanency.
Caudle, Alyssa
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Nutrition & DiabetesBackground Type 2 diabetes mellitus (T2DM) is currently a major global public health problem. Although disease remission is possible, few biomarkers have been identified which can help us select the diet that best promotes remission. Our aim was to study
Juan Francisco Alcala-Diaz +13 more
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Pathogenesis of Atherosclerosis
Journal of the American College of Cardiology, 2006 Atherosclerosis is a multifocal, smoldering, immunoinflammatory disease of medium-sized and large arteries fuelled by lipids. Endothelial cells, leukocytes, and intimal smooth muscle cells are the major players in the development of this disease. The most devastating consequences of atherosclerosis, such as heart attack and stroke, are caused by ...
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Scientific Reports, 2018 Several epidemiological studies report a positive correlation between hyperuricemia and metabolic syndrome (MetS) in adults, which hyperuricemic subjects seem to more easily develop.
Arrigo Francesco Giuseppe Cicero +6 more
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Association of Cytomegalovirus DNA and Immunologic Markers of Cardiovascular Disease. [PDF]
, 2019 BackgroundPersons living with human immunodeficiency virus (HIV) (PLWH) with high cytomegalovirus (CMV)-specific interferon (IFN) γ response have increased numbers of endothelium homing receptor (CX3CR1)+-expressing cells that are associated with ...
Garg, Ankita +4 more
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Clinical Case ReportsAcute aortic dissection is a rare but life‐threatening syndrome, being accompanied by a mortality rate of 1%–2% per hour after the onset of symptoms if they remain untreated.
Yousef Torfi Alaivi +4 more
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