Results 111 to 120 of about 473,671 (315)

Stimulation of alpha 7 nicotinic acetylcholine receptor (α7nAChR) inhibits atherosclerosis via immunomodulatory effects on myeloid cells

open access: yes, 2019
Alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation can regulate acute inflammation, and lack of α7nAChR accelerates atherosclerosis in mice.
Gutiérrez, Saray,   +10 more
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

open access: yesAdvanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen   +19 more
wiley   +1 more source

MicroRNA-223 inhibits tissue factor expression in vascular endothelial cells

open access: yes, 2014
Objective: Atherosclerosis is a chronic inflammatory process, in which vascular endothelial cells (ECs) become dysfunctional owing to the effects of chemical substances, such as inflammatory factor and growth factors.
Cao, Chengfu   +17 more
core   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

Cardiovascular Risk Factors: A Study on the Prevalence of MS among 11-18 Years Old School Children in East of Iran, 2012

open access: yesNutrition and Food Sciences Research, 2015
Background and Objectives: Metabolic syndrome (MS) is associated with increased risk of cardiovascular disorders. MS is increasing among adolescents. This study was conducted to determine the prevalence of MS in 11-18 years old Birjandi school children ...
Fatemeh Taheri   +5 more
doaj  

Atherosclerosis [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2015
Hong, Lu, Alan, Daugherty
openaire   +2 more sources

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li   +16 more
wiley   +1 more source

Alterations of the plasma lipoproteins and apoproteins following cholesterol feeding in the rat

open access: yesJournal of Lipid Research, 1977
The feeding of cholesterol to rats resulted in marked alterations in the type and distribution of the plasma lipoproteins and their apoproteins. The hyperlipoproteinemia was characterized by an increase in the d < 1.006 lipoproteins (B-VLDL and VLDL), an
R W Mahley, K S Holcombe
doaj   +1 more source

Coronary atherosclerosis detected by coronary CT angiography in asymptomatic subjects with early chronic kidney disease

open access: yes, 2010
OBJECTIVES: The purpose of this study is to assess the independent association between early CKD (stages 1-3a) with coronary atherosclerosis and the feasibility of risk stratification of coronary atherosclerosis according to The Kidney Disease Outcomes ...
장혁재
core   +1 more source

VEGF overexpression in atherosclerosis [PDF]

open access: yes, 2023
Diabetes mellitus is a chronic disease that can lead to severe complications, including an increased risk of cardiovascular disease. The underlying mechanisms that link diabetes to the development of vascular complications are not fully understood ...
Talpe Guruge, Rangana
core  

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