Results 111 to 120 of about 999,481 (385)

Pathogenesis of Atherosclerosis

Journal of the American College of Cardiology, 2006
Atherosclerosis is a multifocal, smoldering, immunoinflammatory disease of medium-sized and large arteries fuelled by lipids. Endothelial cells, leukocytes, and intimal smooth muscle cells are the major players in the development of this disease. The most devastating consequences of atherosclerosis, such as heart attack and stroke, are caused by ...
openaire   +4 more sources

Moyamoya Disease and the Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo, Jeong‐Yong Shin, Rugyeom Lee, Jiwon Cheon, Ji Hun Kim, Doeun Kim, Jae‐Kyung Won, In‐Hwan Oh, Yunjong Lee, Tae‐Beom Ahn   +9 more
wiley   +1 more source

Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-).

Journal of Lipid Research, 1994
Using ion exchange high pressure liquid chromatography, total plasma low density lipoprotein (LDL) from 30 hypercholesterolemic and 10 normocholesterolemic cynomolgus monkeys was subfractionated into unmodified LDL (n-LDL) and more negatively charged LDL
H.N. Hodis, D.M. Kramsch, P. Avogaro, G. Bittolo-Bon, G. Cazzolato, J. Hwang, H. Peterson, A. Sevanian   +7 more
doaj   +1 more source

MicroRNAs in atherosclerosis

The Kaohsiung Journal of Medical Sciences, 2012
AbstractMicroRNAs are endogenously expressed small noncoding RNAs that regulate gene expression at the post‐transcriptional level. MicroRNAs have emerged as key regulators of several physiological and pathophysiological processes in the cardiovascular system.
Ku Chung Chen, Suh-Hang Hank Juo
openaire   +4 more sources

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Oral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice[S]

Journal of Lipid Research, 2010
We have shown that Ac-hE18A-NH2, a dual-domain cationic apolipoprotein-mimetic peptide, reduces plasma cholesterol levels in dyslipidemic mice. Two single-domain cationic peptides based on the lytic class L peptide 18L were developed to test the ...
Shaila P. Handattu, Geeta Datta, Richard M. Epand, Raquel F. Epand, Mayakonda N. Palgunachari, Vinod K. Mishra, Candyce E. Monroe, Tamara D. Keenum, Manjula Chaddha, G.M. Anantharamaiah, David W. Garber   +10 more
doaj   +1 more source

An intriguing autopsy case of gangrene intestine [PDF]

, 2006
Background Hashimoto’s thyroiditis is one of the most common causes of hypothyroidism. Hypothyroidism is a known cause of hyperlipidemia. There is a strong correlation between coronary and mesenteric vessel atherosclerosis.
E., E.Jayashankar, Patnayak, Rashmi Patnayak, Prayaga, Aruna K. Prayaga, Reddy, Rajasekhar Reddy, S.V.N., S.V.N. Anuradha   +4 more
core  

The metabolic syndrome adds utility to the prediction of mortality over its components: The Vietnam Experience Study [PDF]

, 2009
Background\ud The metabolic syndrome increases mortality risk. However, as “non-affected” individuals may still have up to two risk factors, the utility of using three or more components to identify the syndrome, and its predictive advantage over ...
Anna C. Phillips, Ardern, Batty, Batty, Catharine R. Gale, Douglas Carroll, Eberly, Ford, Ford, G. David Batty, G. Neil Thomas, Ho, Hu, Hunt, Isomaa, Kannel, Katzmarzyk, Lakka, Malik, Onat, Sattar, Simons, Smith, Sundstrom, Sundström   +24 more
core   +1 more source

ATHEROSCLEROSIS

International Journal of Clinical Practice, 1993
George Payling Wright was Professor of Pathology at Guy's Hospital when I went there as a student in 1941 and I came to know him in 1943. He was a great man, a great scholar and an inspired teacher. Of unimpressive appearance, it was only when he began to lecture or to explain or to demonstrate that his great abilities became apparent.
openaire   +2 more sources

Hydroxychloroquine Associated with Lower Glomerular Filtration Rate Decline in Lupus Nephritis

Arthritis Care &Research, Accepted Article.
Background Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical. Therefore, we analyzed data from our
Shivani Garg, Brad Rovin, Brad C. Astor, Tripti Singh, Fauzia Hollnagel, Megan Kuik, Lexie Kolton, Callie Saric, S. Sam Lim, Christie M. Bartels   +9 more
wiley   +1 more source