Results 141 to 150 of about 782,334 (339)

Design and development of Branched Poly(ß-aminoester) nanoparticles for Interleukin-10 gene delivery in a mouse model of atherosclerosis

, 2022
Nicholas Distasio, France Dierick, Talin Ebrahimian, Maryam Tabrizian, Stéphanie Lehoux   +4 more
openalex   +1 more source

Deciphering Macrophage Phenotypes upon Lipid Uptake and Atherosclerosis [PDF]

, 2020
Jihye Lee, Jae‐Hoon Choi
openalex   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu, Chao Xue, Yang Zhao, Jinjian Sun, Changzhi Zhao, Xu Zhang, Guizhen Zhao, Yaozhong Liu, Hongyu Liu, Yongjie Deng, Ying Wang, Chi Zhang, Yingjie Liu, Linjun Zeng, Ying Yang, Bolun Li, Shusi Ding, Linkang Zhou, Henry Kuang, Zanxin Wang, Wenhao Ju, Haihuan Lin, Jie Lin, Yanhong Guo, Lin Chang, Hongmei Zhao, Jing Wang, Jiandie Lin, Lemin Zheng, Y. Eugene Chen, Jifeng Zhang   +30 more
wiley   +1 more source

Serum uric acid predicts incident metabolic syndrome in the elderly in an analysis of the Brisighella Heart Study

Scientific Reports, 2018
Several epidemiological studies report a positive correlation between hyperuricemia and metabolic syndrome (MetS) in adults, which hyperuricemic subjects seem to more easily develop.
Arrigo Francesco Giuseppe Cicero, Federica Fogacci, Marina Giovannini, Elisa Grandi, Martina Rosticci, Sergio D’Addato, Claudio Borghi   +6 more
doaj   +1 more source

Acculturation Strategies Among South Asian Immigrants: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study [PDF]

, 2016
Belinda L. Needham, Bhramar Mukherjee, Pramita Bagchi, Catherine Kim, Arnab Mukherjea, Namratha R. Kandula, Alka M. Kanaya   +6 more
openalex   +1 more source

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, EarlyView.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

Cabrol Procedure in Complex Aortic Root Reconstruction: A Case Series of Three Young Patients With Acute Aortic Syndrome

Clinical Case Reports
Acute aortic dissection is a rare but life‐threatening syndrome, being accompanied by a mortality rate of 1%–2% per hour after the onset of symptoms if they remain untreated.
Yousef Torfi Alaivi, Seyed Mohammad Hassan Adel, Amanollah Heidari, Nehzat Akiash, Fateme Jorfi   +4 more
doaj   +1 more source

Performance of glomerular filtration rate estimating equations in a community-based sample of Blacks and Whites: the multiethnic study of atherosclerosis [PDF]

, 2017
Lesley A. Inker, Andrew S. Levey, Hocine Tighiouart, Tariq Shafi, John H. Eckfeldt, Craig Johnson, Aghogho Okparavero, Wendy S. Post, Josef Coresh, Michael G. Shlipak   +9 more
openalex   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

Circulating long non-coding RNAs as predictors of type 2 diabetes mellitus development: results from the CORDIOPREV study

Cardiovascular Diabetology
Background Type 2 diabetes mellitus (T2DM) is a growing global health challenge. Conventional diagnostic tools have limited sensitivity and specificity for early-stage disease.
Hatim Boughanem, María José Párraga-Viúdez, Ana Ojeda-Rodríguez, Juan Luis Romero-Cabrera, Eugenia Ruiz-Díaz Narváez, Alejandro López-Moreno, José David Torres-Peña, Manuel Macías-González, Juan Francisco Alcalá-Díaz, Antonio Pablo Arenas-de Larriva, Pablo Pérez-Martínez, Javier Delgado-Lista, José López-Miranda, Oriol Alberto Rangel-Zuñiga   +13 more
doaj   +1 more source