Results 251 to 260 of about 793,722 (339)

20. CORRELATION OF AORTIC DISTENSIBILITY WITH CORONARY ATHEROSCLEROSIS IN ANGINA PATIENTS

, 2009
Gwang-Sil Kim, Young-Sub Byun, Byoung Kwon Lee, Choong-Won Goh, Kun-Joo Rhee   +4 more
openalex   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Association between atherosclerosis-related indicators and fatty liver: a population-based observational study. [PDF]

Eur J Med Res
Liu X, Yuan P, Huang Y.
europepmc   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

Unraveling atherosclerosis through single-cell RNA sequencing: insights into cellular heterogeneity and disease mechanisms. [PDF]

Einstein (Sao Paulo)
Serrano CV, Ribeiro ML, Bichuette LD, Matuck BRS, Severino P, Gollob KJ, Lima JAC, Libby P.   +7 more
europepmc   +1 more source

Additional file 3: Table S3. of Systematic analysis of the molecular mechanism underlying atherosclerosis using a text mining approach

, 2016
Dan Xi, Jinzhen Zhao, Wenyan Lai, Zhigang Guo   +3 more
openalex   +1 more source

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen, Wei Liu, Dan Zhou, Shuhua Liu, Yalun Guan, Zongyu Miao, Lei Cai, Xuejiao Li, Yunfeng Li, Zhongqiang Huang, Yi Jin, Ge Li, Yu Zhang   +12 more
wiley   +1 more source

Correction: Sepsis and obesity: a scoping review of diet-induced obesity murine models

Intensive Care Medicine Experimental
Mikaela Eng, Keshikaa Suthaaharan, Logan Newton, Fatima Sheikh, Alison Fox-Robichaud, the National Preclinical Sepsis Platform, Sepsis Canada   +5 more
doaj   +1 more source

Decoding the Kruppel-like Transcription Factors in Atherosclerosis: Insight from Molecular and Translational Perspectives. [PDF]

Int J Mol Sci
Cao Y, Wang C, Zhu X, Zhan M, Xu J, Jiang M.   +5 more
europepmc   +1 more source

Supplementary Material for: L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women

, 2018
Joanna J. Samulak, Angelika K. Sawicka, Dace Hartmane, Solveiga Grı̄nberga, Osvalds Pugovičs, Wiesława Łysiak−Szydłowska, Robert A. Olek   +6 more
openalex   +1 more source