Results 281 to 290 of about 620,434 (340)

Targeted drug delivery systems for atherosclerosis. [PDF]

open access: yesJ Nanobiotechnology
Tu L   +7 more
europepmc   +1 more source

En Route Toward Sustainable Polycarbonates via Large Cyclic Carbonates

open access: yesChemSusChem, EarlyView.
The use of safe carbonylating agents, allowed by a suitable (bio)catalytic systems, affords the sustainable and green synthesis of large‐ring cyclic carbonates by reaction of renewables such as bio‐based diols. These carbonates are prone to ring‐opening polymerization paving the way for the production of circular aliphatic polycarbonates.
Francesco Della Monica   +5 more
wiley   +1 more source

Synthesis of 19‐Hydroxyarachidonic Acid by Fungal Peroxygenases: An Experimental and Computational Study

open access: yesChemSusChem, EarlyView.
An experimental and computational investigation on the regio‐ and enantioselective hydroxylation of arachidonic acid by several unspecific peroxygenases (UPOs) revealed rAaeUPO A77L variant as the most attractive candidate for the selective production of valuable hydroxy‐fatty acids because of its enhanced regio and enantioselectivity and reduced ...
Alejandro González‐Benjumea   +7 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu   +3 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

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