Results 71 to 80 of about 994,628 (384)

INSULIN AND ATHEROSCLEROSIS

The Lancet, 1969
The idea that excessive concentrations of insulin might contribute to the development of atherosclerosis appeared in the mid 1960s and the evidence was first reviewed in a paper published in 1969 [1]. Since then, data, both clinical and experimental, has continued to accumulate, most of it supportive of the hypothesis, although some of the details have
openaire   +4 more sources

Lymphocytes in atherosclerosis [PDF]

Clinica Chimica Acta, 2012
It is well established that atherosclerosis is caused by an inflammatory process in the arterial intima. However, it is only in recent years that it has become clear that this inflammation is modulated by immune responses against plaque antigens. These antigens are primarily believed to be modified self-antigens such as oxidized LDL.
Wigren, Maria, Nilsson, Jan, Kolbus, Daniel   +2 more
openaire   +5 more sources

Lipolysis-induced partitioning of free fatty acids to lipoproteins: effect on the biological properties of free fatty acids.

Journal of Lipid Research, 1995
Free fatty acids (FFA) released during the lipolysis of triglyceride (TG)-rich lipoproteins in vivo are generally believed to be bound to serum albumin.
B H Chung, G A Tallis, B H Cho, J P Segrest, Y Henkin   +4 more
doaj   +1 more source

Apolipoprotein E related Co-Morbidities and Alzheimer’s disease [PDF]

, 2016
The primary goal of advancement in clinical services is to provide a health care system that enhances an individual’s quality of life. Incidence of diabetes mellitus, cardiovascular disease and associated dementia coupled with the advancing age of the ...
Akiyama, Alharbi, Armitage, Armitage, Armitage, Balin, Barbieri, Bergdahl, Berliner, Borilova Linhartova, Borrell-Pages, Bowling, Braak, Braak, Brown, Bu, Buchanan, Burt, Cambell, Cavrini, Chiu, Chukkapalli, Chukkapalli, Chukkapalli, Cole, Corder, Corrada, Curtiss, Cutler, De Oliveira, DeFronzo, DeStefano, Desvarieux, Duarte, Epel, Farrer, Forner, Foster, Freitag-Wolf, Galbraith, Gan, Gao, Genco, Grehan, Grossi, Habib, Haffajee, Hajishengalis, Hajishengalis, Haraszthy, Hardardottir, Hardy, Harold, Harper, Hayashi, Hayden, Heiduschka, Helfand, Het, Hitt, Holt, Hu, Huang, Hunter, Hutton, Imhof, Iqbal, Itzhaki, Jagannathachary, Joiner, Kamer, Kamer, Kamer, Katz, Khovidhunkit, Klein, Kliegel, Kolovou, Kornman, Kozarov, Kubota, Lalla, Lambert, Lesne, Leszcynska, Libby, Machado, Mahley, Mahley, Mahley, Mahley, Maney, Marti, McGeer, Michalowicz, Miklossy, Miklossy, Miller, Mooradian, Moutsopoulos, Nagpal, Neto, Nicoll, Noble, Okuda, Olsen, Ono, O’Brien, Papapanou, Perls, Pitas, Pizzo, Poirier, Poling, Poole, Poole, Rivera, Riviere, Rogers, Rohn, Roses, Roses, Rowe, Saito, Saunders, Scannapieco, Schuett, Shao, Singhrao, Singhrao, Singhrao, Singhrao, Small, Smit, Socransky, Soscia, Stein, Strittmatter, Strittmatter, Sullivan, Velsko, Walsh, Walsh, Watkins, Weisgraber, Wetterau, Wilson, Young   +147 more
core   +1 more source

Inflammation, Atherosclerosis and Coronary Artery Disease

Clinical Medicine Insights: Cardiology, 2014
Article types include original clinical and basic research articles, case reports, commentaries, meeting reports, methodology, perspectives. Research into inflammation, atherosclerosis and coronary artery disease, including observational studies ...
Y. Momiyama, H. Adachi, D. Fairweather, N. Ishizaka, Emi Saita   +4 more
semanticscholar   +1 more source

Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

Nature Communications, 2020
Vascular disease remains the leading cause of death and disability, the etiology of which often involves atherosclerosis. The current treatment of atherosclerosis by pharmacotherapy has limited therapeutic efficacy.
Cheng Gao, Qiaoxian Huang, Conghui Liu, Cheryl H. T. Kwong, Ludan Yue, J. Wan, S. M. Lee, Ruibing Wang   +7 more
semanticscholar   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Atherosclerosis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2015
Mechanistic studies over the past decades using in vitro systems, animal models, and human tissues have highlighted the complexity of pathophysiological processes of atherosclerosis. Hypercholesterolemia, as one of the major risk factors for the development and progression of atherosclerosis, is still the focus of many mechanistic studies and the major
Hong Lu, Alan Daugherty
openaire   +3 more sources

Computational Modelling of Atherosclerosis

, 2015
Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk from elevated ...
Baldrick, Francina R, McGilligan, Victoria, OKane, Maurice, Parton, Andrew, Watterson, Steven   +4 more
core   +1 more source

Is there a role for thoracic aortic calcium to fine-tune cardiovascular risk prediction? [PDF]

, 2012
Screening asymptomatic subjects to streamline measures for the prevention of cardiovascular events remains a major challenge. The established primary prevention risk-scoring methods use equations derived from large prospective cohort studies, but further
Birgelen, C. von, Hartmann, M.
core   +3 more sources