Results 71 to 80 of about 620,434 (340)

Telomere length as biomarker of nutritional therapy for prevention of type 2 diabetes mellitus development in patients with coronary heart disease: CORDIOPREV randomised controlled trial

Cardiovascular Diabetology
Background Telomere Length (TL), a marker of cellular aging, holds promise as a biomarker to elucidate the molecular mechanism of diabetes. This study aimed to investigate whether shorter telomeres are associated with a higher risk of type 2 diabetes ...
Ana Ojeda-Rodriguez, Oriol A. Rangel-Zuñiga, Antonio P. Arenas-de Larriva, Francisco M. Gutierrez-Mariscal, Jose D. Torres-Peña, Juan L. Romero-Cabrera, Alicia Podadera-Herreros, Helena García-Fernandez, Esther Porras-Pérez, Raul M. Luque, Stefanos N. Kales, Pablo Perez-Martinez, Javier Delgado-Lista, Elena M. Yubero-Serrano, Jose Lopez-Miranda   +14 more
doaj   +1 more source

Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6

Nature Reviews Cardiology, 2020
The number of old people is rising worldwide, and advancing age is a major risk factor for atherosclerotic cardiovascular disease. However, the mechanisms underlying this phenomenon remain unclear.
D. Tyrrell, D. Goldstein
semanticscholar   +1 more source

ATHEROSCLEROSIS

International Journal of Clinical Practice, 1993
George Payling Wright was Professor of Pathology at Guy's Hospital when I went there as a student in 1941 and I came to know him in 1943. He was a great man, a great scholar and an inspired teacher. Of unimpressive appearance, it was only when he began to lecture or to explain or to demonstrate that his great abilities became apparent.
openaire   +2 more sources

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin

Data in Brief, 2016
The data presented in this article describe an effect of N-acetylneuraminic acid and/or quercetin on the inflammatory proteins expressions (TNF-α, ICAM-1, VCAM-1 and MOMA-2) and the N-acetylneuraminic acid (NANA) levels of apolipoprotein E-deficient mice
Rongrong Dong, Fahui Li, Shucun Qin, Yi Wang, Yanhong Si, Xuelian Xu, Hua Tian, Lei Zhai, Guangjie Zhang, Yongjun Li, Yawei Zhou, Ying Zhang, Nan Zhang, Shoudong Guo   +13 more
doaj  

Identification of apoB‐100 Peptide‐Specific CD8+ T Cells in Atherosclerosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundT cells are found in atherosclerotic plaques, with evidence supporting a potential role for CD8+ T cells in atherogenesis. Prior studies provide evidence of low‐density lipoprotein and apoB‐100 reactive T cells, yet specific epitopes relevant ...
Paul C. Dimayuga, Xiaoning Zhao, Juliana Yano, Wai Man Lio, Jianchang Zhou, Peter M. Mihailovic, Bojan Cercek, Prediman K. Shah, Kuang‐Yuh Chyu   +8 more
doaj   +1 more source

Carotid Thrombosis in a Crack Cocaine Smoker Woman

Case Reports in Vascular Medicine, 2020
Introduction. We report a case of stroke in a crack smoker with occlusion of the middle cerebral artery and a large thrombus in the carotid artery. Case Presentation.
Mattia Cosenza, Luigi Panza, Anna Paola Califano, Carolina Defendini, Maria D’Andria, Roberto Romiti, Antonio Fabio Massimo Vainieri, Sergio Morelli   +7 more
doaj   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Adipose tissue cholesteryl ester transfer protein mRNA in response to probucol treatment: cholesterol and species dependence

Journal of Lipid Research, 1993
Probucol treatment results in an increase in plasma concentrations of cholesteryl ester transfer protein (CETP) which may account, in part, for the effects of this agent on plasma concentrations of HDL cholesterol. We have examined the mechanism by which
EM Quinet, P Huerta, D Nancoo, AR Tall, YL Marcel, R McPherson   +5 more
doaj  

A prospective natural-history study of coronary atherosclerosis.

New England Journal of Medicine, 2011
BACKGROUND Atherosclerotic plaques that lead to acute coronary syndromes often occur at sites of angiographically mild coronary-artery stenosis. Lesion-related risk factors for such events are poorly understood.
G. Stone, A. Maehara, A. Lansky, B. de Bruyne, Ecaterina Cristea, G. Mintz, R. Mehran, J. Mcpherson, Naim Z. Farhat, S. Marso, H. Parise, B. Templin, Roseann M. White, Zhen Zhang, P. Serruys   +14 more
semanticscholar   +1 more source