Results 61 to 70 of about 514,218 (262)

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali, Waqar Ahmed Cheema, Fiza Nisar, Muhammad Shamoon, Sameen Sarfaraz, Ahmad Butt, Muhammad Abdullah Ali, Armaghana Abdullah, Muhammad Asad Shabbir, Muhammad Talha, Hammad Azam, Aimen Anwaar Pannun, Usama Saleem, Anousha Tanveer, Mukesh Sharma   +14 more
wiley   +1 more source

Plasma lipoprotein distribution of apoC-III in normolipidemic and hypertriglyceridemic subjects: comparison of the apoC-III to apoE ratio in different lipoprotein fractions

Journal of Lipid Research, 1997
In order to assess the relationship between plasma accumulation of triglyceride-rich lipoproteins (TRL) and lipoprotein levels of apoC-III and apoE, we have measured apoC-III and apoE in lipoproteins separated according to size (by automated gel ...
A Fredenrich, L M Giroux, M Tremblay, L Krimbou, J Davignon, J S Cohn   +5 more
doaj   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source

Oral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice[S]

Journal of Lipid Research, 2010
We have shown that Ac-hE18A-NH2, a dual-domain cationic apolipoprotein-mimetic peptide, reduces plasma cholesterol levels in dyslipidemic mice. Two single-domain cationic peptides based on the lytic class L peptide 18L were developed to test the ...
Shaila P. Handattu, Geeta Datta, Richard M. Epand, Raquel F. Epand, Mayakonda N. Palgunachari, Vinod K. Mishra, Candyce E. Monroe, Tamara D. Keenum, Manjula Chaddha, G.M. Anantharamaiah, David W. Garber   +10 more
doaj   +1 more source

Hepatitis B Virus Seropositivity Is Not Associated with Increased Risk of Carotid Atherosclerosis in Taiwanese

, 2008
Background: Chronic infection has been proposed to increase the risk of atherosclerosis in several experimental and epidemiological studies. However, the relationship of chronic hepatitis B vir-us (HBV) infection and atherosclerosis remains Controversial.
YANG, KAI-CHIEN;CHEN, MING-FONG;SU, TA- CHEN;JENG, JIANN-SHING;LIN, LIAN-YU;LIAU, CHIAU-SUONG;LEE, YUAN-THE, 楊鎧鍵;陳明豐;蘇大成;鄭建興;林亮宇;廖朝崧;李源德   +1 more
core  

Vaccination and atherosclerosis

, 2004
Atherosclerosis is an inflammatory disease. Both innate and adaptive immunity are involved in lesion formation and development. A number of antigen candidates, such as oxidized low-density lipoprotein and heat shock protein, have been associated with the
Hansson, GK, Zhou, X
core   +1 more source

Soluble CD40 receptor is a biomarker of the burden of carotid artery atherosclerosis in subjects at high cardiovascular risk

, 2022
BACKGROUND AND AIMS: The severity of the atherosclerotic burden is hardly quantifiable in subjects at high cardiovascular (CV) risk under intensive pharmacological therapy. Several molecules have been proposed as circulating biomarkers of atherosclerosis,
Baldi, Simona,, Nilsson, Jan,, Natali, Andrea,, Shore, Angela,, Leonetti, Simone,, Tricò, Domenico,, Khan, Faisel,, Kozakova, Michaela,, Goncalves, Isabel,, Lund University., Nesti, Lorenzo,   +10 more
core   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Serum Pon-1 Activity but not Q192R Polymorphism is Related to The Extent of Atherosclerosis

, 2012
Aim: Paraoxonase-1 (PON1) is an antioxidant enzyme located in high density lipoprotein (HDL). PON1 was defined as a protective factor against atherosclerosis.
Tokgözoğlu, S. Lale, Deniz, Ali, Alikasifoglu, Mehmet, Demirpence, Ediz, Bayrak, Tülin, Yavuz, Bunyamin, Volkan-Salancı, Bilge, VOLKAN SALANCI, BİLGE, TOKGÖZOĞLU, SADBERK LALE, Bayrak, Ahmet   +9 more
core   +1 more source

A compound heterozygote for lipoprotein lipase deficiency, Val69–>Leu and Gly188–>Glu: correlation between in vitro LPL activity and clinical expression.

Journal of Lipid Research, 1994
We analyzed the molecular defects in the lipoprotein lipase gene of a patient with type I hyperlipidemia suffering from recurrent pancreatitis, indicative for lipoprotein lipase deficiency.
T. Bruin, S. Tuzgöl, W.J. Mulder, A.E. van den Ende, H. Jansen, M.R. Hayden, J.J. Kastelein   +6 more
doaj   +1 more source