Results 71 to 80 of about 514,218 (262)
Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice [PDF]
, 2014 The reactive dicarbonyls, glyoxal and methylglyoxal (MG), increase in diabetes and may participate in the development of diabetic complications. Glyoxal and MG are detoxified by the sequential activities of glyoxalase 1 (GLO1) and glyoxalase 2.
Rabbani, Naila +11 more
core +1 more source
Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu +4 more
wiley +1 more source
, 2011 Background: This Study was designed to elucidate the relationship between chronic kidney disease (CKD), atherosclerotic complications, and the effects oil functional performance in the elderly. Methods: A total of 2431 subjects aged 65 and above from the
林建宇;林亮宇;郭旭格;林昭維 +1 more
core
Arthritis Care &Research, EarlyView.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
VEGF overexpression in atherosclerosis [PDF]
, 2023 Diabetes mellitus is a chronic disease that can lead to severe complications, including an increased risk of cardiovascular disease. The underlying mechanisms that link diabetes to the development of vascular complications are not fully understood ...
Talpe Guruge, Rangana
core +1 more source
Cardiovascular DiabetologyBackground Telomere Length (TL), a marker of cellular aging, holds promise as a biomarker to elucidate the molecular mechanism of diabetes. This study aimed to investigate whether shorter telomeres are associated with a higher risk of type 2 diabetes ...
Ana Ojeda-Rodriguez +14 more
doaj +1 more source
Resialylation of sialic acid deficit vascular endothelium, circulating cells and macromolecules may counteract the development of atherosclerosis: A hypothesis. [PDF]
, 2007 Deficit sialylation of vascular endothelium, circulating cells and macromolecules has been associated with the development of atherosclerosis. On the other hand, an elevated serum level of sialic acid is a long-lasting marker of atherosclerosis and ...
Lindberg, Gunnar
core +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is the cornerstone of systemic lupus erythematosus (SLE) management with benefits extending beyond SLE control, including protection against atherosclerotic cardiovascular disease (ASCVD). Although HCQ blood levels reflect recent exposure and long‐term intake reflects medication adherence, the impact of longitudinal ...
Shivani Garg +5 more
wiley +1 more source
Identification of apoB‐100 Peptide‐Specific CD8+ T Cells in Atherosclerosis
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundT cells are found in atherosclerotic plaques, with evidence supporting a potential role for CD8+ T cells in atherogenesis. Prior studies provide evidence of low‐density lipoprotein and apoB‐100 reactive T cells, yet specific epitopes relevant ...
Paul C. Dimayuga +8 more
doaj +1 more source
Role of LCAT in atherosclerosis
, 2016 Lecithin:cholesterol acyltransferase (LCAT) is the only enzyme capable of esterifying cholesterol in plasma, thus determining the maturation of high-density lipoproteins.
L. Calabresi +4 more
core +1 more source