Results 1 to 10 of about 154,772 (354)

Investigation for atherosclerotic plaque rupture with thrombosis in mice based on single-cell sequencing and bioinformatics analysis. [PDF]

Front Cardiovasc Med
IntroductionAtherosclerotic plaque rupture with thrombus formation leads to severe cardiovascular events. We hoped to explore the hub genes providing critical roles in the process of atherosclerotic plaque rupture accompanied by thrombus formation, which
Nie P, Wan F, Yao T, Li Y, Yan G, Pu J, Jin S.   +6 more
europepmc   +2 more sources

Coronary Artery Disease and Atherosclerosis in Other Vascular Districts: Epidemiology, Risk Factors and Atherosclerotic Plaque Features. [PDF]

Life (Basel)
Coronary artery disease (CAD) is the main cause of morbidity and death worldwide, and atherosclerosis represents the leading pathophysiological pathway responsible for CAD.
Russo M, Gurgoglione FL, Russo A, Rinaldi R, Torlai Triglia L, Foschi M, Vigna C, Vergallo R, Montone RA, Benedetto U, Niccoli G, Zimarino M.   +11 more
europepmc   +2 more sources

Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis. [PDF]

Signal Transduct Target Ther
At advanced phases of atherosclerosis, the rupture and thrombogenesis of vulnerable plaques emerge as primary triggers for acute cardiovascular events and fatalities. Pathogenic infection such as periodontitis-associated Porphyromonas gingivalis (Pg) has
Huang X, Xie M, Wang Y, Lu X, Mei F, Zhang K, Yang X, Chen G, Yin Y, Feng G, Song W, Dong N, Deng X, Wang S, Chen L.   +14 more
europepmc   +2 more sources

Effects of lipid-lowering therapy on coronary atherosclerotic plaque evaluated by intravascular imaging [PDF]

Jichu yixue yu linchuang, 2022
The progression of atherosclerotic plaque is one of the most important causes of cardiovascular events in patients with atherosclerotic cardiovascular diseases (ASCVD).
ZHANG Shuang, LI Zhi-fan, QIAN Jie, WU Na-qiong
doaj   +1 more source

Advances of nanoparticle-mediated diagnostic and theranostic strategies for atherosclerosis

Frontiers in Bioengineering and Biotechnology, 2023
Atherosclerotic plaque remains the primary cause of morbidity and mortality worldwide. Accurate assessment of the degree of atherosclerotic plaque is critical for predicting the risk of atherosclerotic plaque and monitoring the results after intervention.
Lin Lin, Lin Lin, Lin Lin, Lin Chen, Juan Yan, Juan Yan, Peirong Chen, Jiahui Du, Jiahui Du, Junpeng Zhu, Junpeng Zhu, Xinyu Yang, Xinyu Yang, Boxin Geng, Boxin Geng, Lang Li, Lang Li, Wen Zeng, Wen Zeng, Wen Zeng   +19 more
doaj   +1 more source

Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis

Frontiers in Genetics, 2021
Atherosclerosis is a progressive vascular wall inflammatory disease, and the rupture of atherosclerotic vulnerable plaques is the leading cause of morbidity and mortality worldwide.
Peng Nie, Fan Yang, Fang Wan, Shuxuan Jin, Jun Pu   +4 more
doaj   +1 more source

Potential circulating biomarkers of atherosclerotic plaque vulnerability in patients in the early recovery period of atherothrombotic stroke [PDF]

The Ukrainian Biochemical Journal, 2023
Despite the informative value of ultrasound examination of atherosclerotic vascular lesions, predicting­ the plaque vulnerabili­ty remains difficult. Circulating blood biomarkers could provide additional criteria that would allow better determination of ...
O. Ya. Mykhalojko, I. Ya. Mykhalojko
doaj   +1 more source

The Effect of PCSK9 Inhibition on the Stabilization of Atherosclerotic Plaque Determined by Biochemical and Diagnostic Imaging Methods

Molecules, 2023
Atherosclerosis is a multifactorial, progressive, chronic inflammatory disease. Ultrasound and magnetic resonance imaging are the most accurate predictors of atherosclerotic plaque instability (MRI).
Marcin Basiak, Marcin Hachula, Michal Kosowski, Grzegorz Machnik, Mateusz Maliglowka, Maria Dziubinska-Basiak, Robert Krysiak, Boguslaw Okopien   +7 more
doaj   +1 more source

Plasma Testosterone Levels and Atherosclerotic Plaque Gene Expression in Men With Advanced Atherosclerosis

Frontiers in Cardiovascular Medicine, 2021
Aims: Low plasma testosterone levels have been shown to predict worse outcome in men with severe atherosclerotic disease. We hypothesized that a low plasma testosterone level affects disease risk through changes in gene expression in atherosclerotic ...
Floor Groepenhoff, Floor Groepenhoff, Ernest Diez Benavente, Arjan Boltjes, Nathalie Timmerman, Farahnaz Waissi, Robin J. G. Hartman, N. C. Onland-Moret, Gerard Pasterkamp, Hester Den Ruijter   +9 more
doaj   +1 more source

The Applications of Single-Cell RNA Sequencing in Atherosclerotic Disease

Frontiers in Cardiovascular Medicine, 2022
Atherosclerosis still is the primary cause of death worldwide. Our characterization of the atherosclerotic lesion is mainly rooted in definitions based on pathological descriptions.
Lotte Slenders, Daniëlle E. Tessels, Sander W. van der Laan, Gerard Pasterkamp, Michal Mokry, Michal Mokry   +5 more
doaj   +1 more source