Results 41 to 50 of about 283,363 (298)

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Platelet‐Mimicking Therapeutic System for Noninvasive Mitigation of the Progression of Atherosclerotic Plaques

Advanced Science, 2021
Atherosclerotic plaque is the primary cause of cardiovascular disorders and remains a therapeutic hurdle for the early intervention of atherosclerosis. Traditional clinical strategies are often limited by surgery‐related complications or unsatisfactory ...
Yi Ma, Yuxuan Ma, Mengqiu Gao, Zhihao Han, Wen Jiang, Yueqing Gu, Yi Liu   +6 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Investigation for atherosclerotic plaque rupture with thrombosis in mice based on single-cell sequencing and bioinformatics analysis

Frontiers in Cardiovascular Medicine
IntroductionAtherosclerotic plaque rupture with thrombus formation leads to severe cardiovascular events. We hoped to explore the hub genes providing critical roles in the process of atherosclerotic plaque rupture accompanied by thrombus formation, which
Peng Nie, Fang Wan, Tianbao Yao, Yao Li, Guofeng Yan, Jun Pu, Shuxuan Jin   +6 more
doaj   +1 more source

Stages of atherosclerotic plaque development and unstable plaque types: pathophysiologic and histologic characteristics

Российский кардиологический журнал, 2013
This literature review focuses on the modern views on the problem of atherosclerotic plaque, its developmental stages (from the lipid steak to unstable atherosclerotic plaque), and various types of plaque instability (lipid, inflammatory, and ...
Yu. I. Ragino, A. M. Volkov, A. M. Chernyavskyi   +2 more
doaj   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali, Waqar Ahmed Cheema, Fiza Nisar, Muhammad Shamoon, Sameen Sarfaraz, Ahmad Butt, Muhammad Abdullah Ali, Armaghana Abdullah, Muhammad Asad Shabbir, Muhammad Talha, Hammad Azam, Aimen Anwaar Pannun, Usama Saleem, Anousha Tanveer, Mukesh Sharma   +14 more
wiley   +1 more source

Molecular analysis shows the presence of periodontal bacterial DNA in atherosclerotic plaques from patients with coronary artery disease

Indian Heart Journal, 2021
Links between periodontitis and atherosclerosis can be predicted based on inflammatory mechanisms initiated by bacteria associated with periodontal lesions, which then influence the initiation or propagation of the atherosclerotic lesion.
Amita Rao, Caroline D’Souza, K. Subramanyam, Praveen Rai, Biju Thomas, Mundayat Gopalakrishnan, Indrani Karunasagar, Ballamoole Krishna Kumar   +7 more
doaj   +1 more source

Numerical investigation of atherosclerotic plaque rupture using optical coherence tomography imaging and XFEM [PDF]

, 2018
Myocardial infarction contributes to most fatalities in which atherosclerotic plaque disruption is the underlying pathology. From the mechanics view point, the pulsatile blood flow in the arteries resembles a fatigue environment and generates stresses ...
Yarlagadda, Prasad K.D.V., Wang, Jiaqiu, Gu, YuanTong, Paritala, Phani Kumari, Li, Zhiyong   +4 more
core   +1 more source

The Complex Mechanisms and the Potential Effects of Statins on Vascular Calcification: A Narrative Review

Reviews in Cardiovascular Medicine
Vascular calcification (VC) is a complex process of calcium deposition on the arterial wall and atherosclerotic plaques and involves interaction between vascular smooth muscle cells, inflammatory and VC mediators. The latter are independent predictors of
Nikolaos PE Kadoglou, Marianna Stasinopoulou, Nikolaos Velidakis, Elina Khattab, Eirini Christodoulou, Evangelia Gkougkoudi, Georgia Valsami   +6 more
doaj   +1 more source

Calcifications in atherosclerotic plaques and impact on plaque biomechanics

Journal of Biomechanics, 2019
The catastrophic mechanical rupture of an atherosclerotic plaque is the underlying cause of the majority of cardiovascular events. The infestation of vascular calcification in the plaques creates a mechanically complex tissue composite. Local stress concentrations and plaque tissue strength properties are the governing parameters required to predict ...
Barrett, Hilary E., Van der Heiden, Kim, Farrell, Eric, Gijsen, Frank J.H., Akyildiz, Ali C.   +4 more
openaire   +3 more sources