Results 51 to 60 of about 81,889 (265)

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Oral glucose tolerance test predicts increased carotid plaque burden in patients with acute coronary syndrome.

PLoS ONE, 2017
BackgroundType 2 diabetes and prediabetes are established risk factors for atherosclerosis. The aim of this study was to evaluate the atherosclerotic plaque burden in the carotid arteries of patients with acute coronary syndrome according to their ...
Thorarinn A Bjarnason, Steinar O Hafthorsson, Linda B Kristinsdottir, Erna S Oskarsdottir, Thor Aspelund, Sigurdur Sigurdsson, Vilmundur Gudnason, Karl Andersen   +7 more
doaj   +1 more source

Ultrasound methods of imaging atherosclerotic plaque in carotid arteries: examinations using contrast agents

Journal of Ultrasonography, 2020
The primary technique for detecting the presence and monitoring the development of carotid atherosclerotic plaque is ultrasound. The development of ultrasound techniques has made it possible to precisely visualise not only blood flow, but also vessel ...
Fedak Andrzej, Chrzan Robert, Chukwu Ositadima, Urbanik Andrzej   +3 more
doaj   +1 more source

Proteomic analysis of atherosclerotic plaque

Biomedicine & Pharmacotherapy, 2010
Proteins play a fundamental role in the formation and progression of plaque, but proteomic analysis of plaque as a whole is difficult, due to its heterogeneous cellular composition and an abundance of plasma proteins. Several approaches to this problem are reported in the literature; they include proteomic analysis of vascular tissues, analysis of ...
PORCELLI B., CIARI I., FELICI C., PAGANI R., BANFI C., BRIOSCHI M., GIUBBOLINI M., DE DONATO G., SETACCI C., TERZUOLI L.   +9 more
openaire   +5 more sources

Microbial composition of atherosclerotic plaques [PDF]

Oral Diseases, 2014
ObjectiveThe association of infections such as periodontitis with atherosclerotic diseases is well documented. In spite of the high diversity of the human oral microbiota, and its close contact with the circulatory system, few oral species were detected in atherosclerotic plaques.
C A, Calandrini, A C, Ribeiro, A C, Gonnelli, C, Ota-Tsuzuki, L P, Rangel, E, Saba-Chujfi, M P A, Mayer   +6 more
openaire   +2 more sources

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Mechanical Assessment in Atherosclerosis Based on Photoacoustic Viscoelasticity Imaging

Photonics
Early identification of vulnerable plaques is a major challenge in diagnosis and assessment of atherosclerosis. In atherosclerotic plaque development, the proportion change in components caused plaque mechanical property change and induced plaque rupture.
Xingchao Zhang, Xiaohan Shi, Hui Wu, Caixun Bai, Junshan Xiu, Yue Zhao   +5 more
doaj   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation[S]

Journal of Lipid Research, 2013
Lysophosphatidic acid (LPA), a bioactive lysophospholipid, accumulates in the atherosclerotic plaque. It has the capacity to activate mast cells, which potentially exacerbates plaque progression.
Martine Bot, Saskia C.A. de Jager, Luke MacAleese, H. Maxime Lagraauw, Theo J.C. van Berkel, Paul H.A. Quax, Johan Kuiper, Ron M.A. Heeren, Erik A.L. Biessen, Ilze Bot   +9 more
doaj   +1 more source

Macrophage heterogeneity in atherosclerotic plaques [PDF]

Current Opinion in Lipidology, 2009
The varied behaviour of macrophages and foam cells during atherosclerosis and its clinical sequelae prompt the question whether all these activities can be the property of a single cell population.Subsets of monocytes with distinct patterns of surface markers and behaviours during inflammation have recently been characterized and shown to have ...
Johnson, JL, Newby, AC
openaire   +3 more sources