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Intermedin1-53 attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages
Cell Death and Disease, 2021 Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to ...Jin-Ling Ren, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Shi-Meng Liu, Yan-Rong Yu, Mo-Zhi Jia, Chao-Shu Tang, Yong-Fen Qi, Wei-Wei Lu +9 moredoaj +1 more sourceExploration of the atherosclerotic plaque
Biomedicine & Pharmacotherapy, 1990 During the past 3 decades we have achieved a better understanding of the atherosclerotic process. It has been described as a series of changes in the intima of arteries consisting of the focal accumulation of lipids, complex carbohydrates, blood and blood products, fibrous tissues, and calcium that are also associated with changes in the media.J H, Ip, V, Fuster, J H, Chesebroopenaire +2 more sourcesLow adiponectin levels are an independent predictor of mixed and non-calcified coronary atherosclerotic plaques. [PDF]
, 2009 Atherosclerosis is the primary cause of coronary artery disease (CAD). There is increasing recognition that lesion composition rather than size determines the acute complications of atherosclerotic disease.Lebherz Corinna, Renee Stark, Christoph Becker, Stark, R.G., Stark, Renee, Tittus, Janine, Lehrke Michael, Lebherz, C., Greif, Martin, Greif Martin, Broedl Uli C., Reiser, M., Stark Renee, Reiser, Maximilian, Ziegler, Franz von, Alexander W Leber, Göke, B., Parhofer, K.G., Lebherz, Corinna, Alexander Becker, Leber, A.W., Leber, Alexander W., Michael Lehrke, Corinna Lebherz, Lehrke, Michael, Greif, M., von Ziegler Franz, Parhofer Klaus G., von Ziegler, A., Göke, Burkhard, Parhofer, Klaus G., Janine Tittus, Becker, C., Becker Alexander, Broedl, U.C., Reiser Maximilian, Broedl, Uli C., Martin Greif, Klaus G Parhofer, Tittus, J., Tittus Janine, Burkhard Göke, Göke Burkhard, Becker, F., Becker, Alexander, Maximilian Reiser, Uli C Broedl, Becker, Christoph, Becker Christoph, Leber Alexander W., Franz von Ziegler, Lehrke, M. +51 morecore +2 more sourcesRANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies. [PDF]
, 2011 The chemokine RANTES (regulated on activation, normal T-cell expressed and secreted)/CCL5 is involved in the pathogenesis of cardiovascular disease in mice, whereas less is known in humans. We hypothesised that its relevance for atherosclerosis should be Hilma Holm, Poschen Ulrike, Panos Deloukas, Assimes, Themistocles L., Karakas, Mahir, Mahir Karakas, Erdmann, Jeanette, Moll, F.L., Robert Roberts, Illig, T., Samani, Nilesh J, Sekar Kathiresan, Muredach P Reilly, Koenig Wolfgang, Dominique P. V. de Kleijn, Herder, C., Thorand, Barbara, Illig Thomas, Preuss Michael, Pasterkamp, Gerard, Moll Frans L., null null, Ruth McPherson, König, Inke R, Poschen, Ulrike, Samani, Nilesh J., Karakas, M., Thorgeirsson, Gudmundur, de Kleijn Dominique P. V., Preuss, M, Frans L Moll, Alexandre F R Stewart, Meisinger Christa, Koenig, W., Holm, Hilma, de Kleijn, Dominique P. V., CARDIoGRAM Consortium, König, Inke R., Ulrike Poschen, Moll, Frans L, Roberts, Robert, Peeters, Wouter, Koenig, Wolfgang, Karakas Mahir, Müller-Nurasyid, Martina, Jeanette Erdmann, Wouter Peeters, Thorand Barbara, Meisinger, Christa, Herder Christian, Klopp, Norman, Roden, M., Herder, Christian, Moll, Frans L., Roden, Michael, Stewart, Alexandre FR, Gerard Pasterkamp, Heribert Schunkert, Martina Müller-Nurasyid, Müller-Nurasyid, M., Pasterkamp Gerard, Jens Baumert, Roden Michael, Klopp, N., McPherson, Ruth, Reilly, Muredach P, Inke R König, Deloukas, Panos, Schunkert, Heribert, Dominique P V de Kleijn, Kathiresan, Sekar, Wolfgang Koenig, Barbara Thorand, CARDIoGRAM Consortium (Illig, T. ; Wichmann, H.-E. ; Döring, A. ; Peters, A. ; Meitinger, T. ; Klopp, N. ; Meisinger, C.), Müller-Nurasyid Martina, Michael Preuss, Poschen, U., Preuss, Michael, Peeters, W., Illig, Thomas, Baumert, Jens, Reilly, Muredach P., Frans L. Moll, Christian Herder, Thomas Illig, Christa Meisinger, Stewart, Alexandre F. R., Klopp Norman, Meisinger, C., Assimes, Themistocles L, Peeters Wouter, de Kleijn, Dominique PV, Baumert Jens, de Kleijn, D.P., Stewart, Alexandre F R, de Kleijn, Dominique P V, Michael Roden, Themistocles L Assimes, Nilesh J Samani, Norman Klopp, Baumert, J.J., Thorand, B., Pasterkamp, G., Preuss, M., Schunkert, H., Kathiresan, S., Roberts, R., Erdmann, J., König, I.R., Deloukas, P., Assimes, T.L., Samani, N.J., Stewart, A.F., Baumert, J., Holm, H., McPherson, R., Reilly, M.P., Rice, K. (Kenneth), Meisinger, C. (Christa), Duijn, C.M. (Cornelia) van, Sinning, Christoph, Stewart, A.F.R. (Alexandre), Schillert, A. (Arne), Siscovick, D.S. (David), Go, Alan, Quertermous, T. (Thomas), Morrison, A.C. (Alanna), Linsel-Nitschke, P. (Patrick), Fortmann, S.P. (Stephen), Hengstenberg, Christian, Karakas M., Laaksonen, R. (Reijo), Whitteman, J. (Jaqueline), Grammer, T.B. (Tanja), Illig T., Nicaud, V., McPherson R., Peters, A. (Annette), Scharnagl, H. (Hubert), Waksman, R. (Ron), Ramachandran, V.S. (Vasan), Braund, P.S. (Peter), Moll F.L., Wright, B.J. (Benjamin), Chen, L. (Li), Blankenberg, Stefan, Samani N.J., Bis, J.C. (Joshua), Stark, K. (Klaus), Willenborg, C. (Christina), Blankenberg, S. (Stefan), Thorleifsson, G. (Gudmar), Bruse, P. (Petra), Laaksonen, Reijo, Stojakovic, T. (Tatjana), Boerwinkle, Eric, Zeller, Tanja, Dandona, S. (Sonny), Perret, C. (Claire), Meinitzer, A. (Andreas), Nelson, C.P. (Christopher P.), Barbalic, M. (maja), Wichmann, H.E. (Heinz Erich), Poschen U., Rotter, J.I. (Jerome), Illig, T. (Thomas), Tang, Hua, Folsom, A.R. (Aaron), Harris, T.B. (Tamara), Pichard, A.D., Waterworth, D. (Dawn), Wild, P.S. (Philipp), Andersen, K.K. (Karl), Burnett, M.S., Knouff, C.W. (Christopher), Li, Mingyao, Cupples, L.A. (Adrienne), Chen, I.Y.-D. (Ida Yii-Der), Voight, Benjamin F., Munzel, T. (Thomas), Preuss M., Heckbert, S.R. (Susan), Risch, N., Demissie-Banjaw, S. (Serkalem), Erdmann, J. (Jeanette), König, I.R. (Inke), Uitterlinden, Andre; id_orcid, Stewart, Alexandre F.R., Reilly M.P., Hlatky, Mark, Sidney, Steven, Klopp N., Hlatky, M.A. (Mark), Ziegler, A. (Andreas), Smith, N.L. (Nicholas), Rupprecht, H.J., Guiducci, C. (Candace), Stewart A.F., Schwartz, S.M. (Stephen), Wild, Philipp, Lindsay, J.M. (Joseph), van Duijn, Cornelia, Knowles, Joshua, Bickel, H. (Horst), Gretarsdottir, S. (Solveig), Wells, G.A. (George), Zeller, T. (Tanja), Zwart, J-A. (John-Anker), Tomaschitz, A. (Andreas), Hall, Alistair, Halperin, E. (Eran), Schnabel, Renate, Peeters W., Fortmann, Stephen, Winkler, K. (Karl), Cambien, F. (François), Hoffmann, M.M. (Michael), Altshuler, D. (David), Epstein, S.E. (Stephen), Thorsteinsdottir, Unnur, Levy, D. (Daniel), Preuss, M. (Michael), Roberts R., Koenig, W. (Wolfgang), Iribarren, Carlos, M乴ler-Nurasyid M., Koenig W., Hakonarson, H. (Hakon), Boerwinkle, E.A. (Eric), Kent, K.M. (Kenneth), Thompson, J.R. (John), Elosua, R. (Roberto), Lackner, K.J. (Karl), Wagner, A.K. (Arnika), Risch, Neil, Nahrstedt, J. (Janja), Renner, W. (Wilfried), Gudnason, V. (Vilmundur), Hengstenberg, C. (Christian), Walker, M.C. (Max), Cupples, L. Adrienne, Chen, Li, Reilly, M.P. (Muredach), Myers, Richard, McPherson, R. (Ruth), Qu, L. (Liming), Thompson, John R., Kong, A. (Augustine), Rader, D.J. (Daniel), Peltonen, L. (Leena Johanna), Schnabel, R.B. (Renate), Myers, R.H. (Richard), Doering, A. (Angela), Ball, S.G. (Stephen), Uitterlinden, A.G. (André), Wells, George A., Dobnig, H. (Harald), Absher, Devin, Dehghan, A. (Abbas), Hofman, A. (Albert), O'Donnell, C.J. (Christopher), Devaney, J. (Joseph), Quertermous, Thomas, Voight, B.F. (Benjamin), Assimes T.L., Roden M., de Kleijn D.P., Medack, A. (Anja), Sidney, S. (Steven), Schunkert H., Kleber, M. (Martina), Holm H., Jarinova, O. (Olga), Erdmann J., Thorgeirsson, G. (Gudmundur), Dehghan, Abbas, Hall, A. (Anne), Moll, F.L. (Frans), Balmforth, A.J. (Anthony), Mooser, V. (Vincent), März, W. (Winfried), Gabriel, S.B. (Stacey), Glazer, N.L. (Nicole), Roberts, R. (Robert), Thorleifsson, Gudmar, Großhennig, A. (Anika), Ziegler, Andreas, Meisinger C., Tiret, L. (Laurence), Salomaa, V. (Veikko), Melander, O. (Olle), Thorsteinsdottir, U. (Unnur), Matthai, W. (William), Samani, N.J. (Nilesh), Aherrahrou, Z. (Zouhair), Holm, H. (Hilma), Schunkert, H. (Heribert), Psaty, B.M. (Bruce), Thorand B., Tang, H. (Hui), Taylor, K.D. (Kent), Kathiresan S., Lumley, T. (Thomas), Kathiresan, S. (Sekar), Schreiber, S. (Stefan), Knowles, J.W. (Joshua), Sinning, C. (Christoph), Smith, A.V. (Davey), Li, M. (Mingyao), Hofman, Albert, Fischer, M. (Marcus), Deloukas P., Musunuru, K. (Kiran), Böhm, B., Lieb, W. (Wolfgang), Schillert, Arne, Baumert J., Proust, C. (Carole), Musunuru, Kiran, Klopp, N. (Norman), Winkelmann, B., Iribarren, C. (Carlos), Meitinger, T. (Thomas), Halperin, Eran, Go, A.T.J.I. (Attie), Herder C., Pilz, D.T. (Daniela), Loley, C. (Christina), Deloukas, P. (Panagiotis), Satler, L.F., Marciante, K. (Kristin), Gulcher, J.R. (Jeffrey), Pasterkamp G., Burtt, N.P. (Noël), Wilensky, A. (Asaf), K?nig I.R., Lackner, Karl, Volcik, K.A. (Kelly) +337 morecore +2 more sourcesAngiogenesis in the atherosclerotic plaque
Redox Biology, 2017 Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries characterized by a local accumulation of cholesterol and non-resolving inflammation. Atherothrombotic complications are the leading cause of disability and mortality in western countries.Caroline Camaré, Mélanie Pucelle, Anne Nègre-Salvayre, Robert Salvayre +3 moreopenaire +3 more sources