Results 21 to 30 of about 283,363 (298)

Intermedin1-53 attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

open access: yesCell Death and Disease, 2021
Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to ...
Jin-Ling Ren   +9 more
doaj   +1 more source

Comparative study on hemodynamic environments around patient-specific carotid atherosclerotic plaques with different symmetrical features

open access: yesMedicine in Novel Technology and Devices, 2021
Atherosclerotic plaque near the carotid sinus is a key risk factor for ischemic stroke. Although disturbed hemodynamic environments around atherosclerotic plaque had been investigated in many studies, the effect of their symmetrical features, especially ...
Xianghui Gong   +5 more
doaj   +1 more source

Travelling to Rome : inflammation, endoplasmic reticulum stress and angiogenesis during atherosclerotic plaque development [PDF]

open access: yes, 2010
Cardiovascular diseases are the leading cause of death worldwide followed by cancer. Atherosclerosis, the major underlying cause of cardiovascular diseases, is a syndrome affecting medium-sized and large arteries.
Kyriakakis, Emmanouil
core   +1 more source

Exploration of the atherosclerotic plaque

open access: yesBiomedicine & Pharmacotherapy, 1990
During the past 3 decades we have achieved a better understanding of the atherosclerotic process. It has been described as a series of changes in the intima of arteries consisting of the focal accumulation of lipids, complex carbohydrates, blood and blood products, fibrous tissues, and calcium that are also associated with changes in the media.
J H, Ip, V, Fuster, J H, Chesebro
openaire   +2 more sources

Low adiponectin levels are an independent predictor of mixed and non-calcified coronary atherosclerotic plaques. [PDF]

open access: yes, 2009
Atherosclerosis is the primary cause of coronary artery disease (CAD). There is increasing recognition that lesion composition rather than size determines the acute complications of atherosclerotic disease.
Lebherz Corinna   +51 more
core   +2 more sources

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies. [PDF]

open access: yes, 2011
The chemokine RANTES (regulated on activation, normal T-cell expressed and secreted)/CCL5 is involved in the pathogenesis of cardiovascular disease in mice, whereas less is known in humans. We hypothesised that its relevance for atherosclerosis should be
Hilma Holm   +337 more
core   +2 more sources

Atherosclerosis and Atheroma Plaque Rupture: Imaging Modalities in the Visualization of Vasa Vasorum and Atherosclerotic Plaques

open access: yesThe Scientific World Journal, 2014
Invasive angiography has been widely accepted as the gold standard to diagnose cardiovascular pathologies. Despite its superior resolution of demonstrating atherosclerotic plaque in terms of degree of lumen stenosis, the morphological assessment for the ...
Zhonghua Sun
doaj   +1 more source

Angiogenesis in the atherosclerotic plaque

open access: yesRedox Biology, 2017
Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries characterized by a local accumulation of cholesterol and non-resolving inflammation. Atherothrombotic complications are the leading cause of disability and mortality in western countries.
Caroline Camaré   +3 more
openaire   +3 more sources

Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques

open access: yesFrontiers in Neurology, 2023
Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation.
Zhiwei He   +6 more
doaj   +1 more source

High-Resolution MRI of Intracranial Atherosclerotic Disease [PDF]

open access: yesNeurointervention, 2014
Intracranial atherosclerotic disease (ICAD) causes up to 10% of all ischemic strokes, and the rate of recurrent vascular ischemic events is very high. Important predictors of vulnerability in atherosclerotic plaques include the degree of stenosis and the
Chang-Woo Ryu   +3 more
doaj   +1 more source

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