Results 161 to 170 of about 510,672 (398)

A proposed structure of chondroitin 6-sulfate proteoglycan of human normal and adjacent atherosclerotic plaque. [PDF]

, 1986
William D. Wagner, G J Salisbury, H. Rowe   +2 more
openalex   +1 more source

Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability

Aging Cell, 2015
It is now thought that atherosclerosis, although due to increased plasma lipids, is mainly the consequence of a complicated inflammatory process, with immune responses at the different stages of plaque development.
S. Gargiulo, P. Gamba, G. Testa, Daniela Rossin, F. Biasi, G. Poli, G. Leonarduzzi   +6 more
semanticscholar   +1 more source

HDL‐C/LDL‐C Ratio and All‐Cause Mortality in Populations at High CVD Risk: A Prospective Observational Cohort Study

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background The ratio of high‐density lipoprotein cholesterol (HDL‐C) to low‐density lipoprotein cholesterol (LDL‐C) predicts cardiovascular disease (CVD) endpoints, yet its prognostic validity in high‐risk populations and for type 2 diabetes mellitus (T2DM)‐related adverse events remains unestablished. Methods This study included 32,609 people
Biting Lin, Yunzhi Ling, Gengyu Zhou, Ziqing Ruan, Fan Chen, Simiao Chen, Tingting Weng, Yuanfan Zhu, Jingyi Lin, Lin Yu, Kaiyang Lin   +10 more
wiley   +1 more source

Glycosaminoglycans in the human aorta in diabetes mellitus: a study of tunica media from areas with and without atherosclerotic plaque [PDF]

, 1994
Lene Heickendorff, T. Ledet, Lars Melholt Rasmussen   +2 more
openalex   +1 more source

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

ChemMedChem, EarlyView.
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore, Carmen Festa, Rosa Barbato, Stefano Fiorucci, Angela Zampella, Simona De Marino   +5 more
wiley   +1 more source

Electrical impedance of layered atherosclerotic plaques on human aortas [PDF]

, 1992
C. J. Slager, A.C. Phaff, C. E. Essed, N. Bom, Johan C.H. Schuurbiers, Patrick W. Serruys   +5 more
openalex   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation[S]

Journal of Lipid Research, 2013
Lysophosphatidic acid (LPA), a bioactive lysophospholipid, accumulates in the atherosclerotic plaque. It has the capacity to activate mast cells, which potentially exacerbates plaque progression.
Martine Bot, Saskia C.A. de Jager, Luke MacAleese, H. Maxime Lagraauw, Theo J.C. van Berkel, Paul H.A. Quax, Johan Kuiper, Ron M.A. Heeren, Erik A.L. Biessen, Ilze Bot   +9 more
doaj  

Atherosclerotic plaques: Advances in imaging for sequential quantitative evaluation [PDF]

, 1994
D. Eugene Strandness
openalex   +1 more source

Folate Receptor–Targeted Single-Photon Emission Computed Tomography/Computed Tomography to Detect Activated Macrophages in Atherosclerosis: Can It Distinguish Vulnerable from Stable Atherosclerotic Plaques?

Molecular Imaging, 2014
The need for noninvasive imaging to distinguish stable from vulnerable atherosclerotic plaques is evident. Activated macrophages play a role in atherosclerosis and express folate receptor folate receptor β (FR-β).
Leah C.J. Winkel, Harald C. Groen, Bibi S. van Thiel, Cristina Müller, Antonius F.W. van der Steen, Jolanda J. Wentzel, Marion de Jong, Kim Van der Heiden   +7 more
doaj   +1 more source