Results 21 to 30 of about 146,166 (354)

Intermedin1-53 attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

open access: yesCell Death and Disease, 2021
Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to ...
Jin-Ling Ren   +9 more
doaj   +1 more source

Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque [PDF]

open access: yes, 2018
Experimental studies showed that gut-derived lipopolysaccharide (LPS) is pro-atherogenic, however, its relationship with human atherosclerosis is still to be defined.
Cammisotto, Vittoria   +11 more
core   +2 more sources

Imaging the carotid atherosclerotic plaque [PDF]

open access: yesVascular Biology, 2019
This mini review provides a concise overview of imaging techniques that are currently used to image the atheroscletoric plaque in the carotid artery in vivo. The main techniques include ultrasound imaging, X-ray imaging, magnetic resonance imaging and positron emission tomography imaging.
Elena Giulia Milano   +5 more
openaire   +3 more sources

Research Progress on the Risk Factors and Outcomes of Human Carotid Atherosclerotic Plaques

open access: yesChinese Medical Journal, 2017
Objective: Atherosclerosis is an inflammatory process that results in complex lesions or plaques that protrude into the arterial lumen. Carotid atherosclerotic plaque rupture, with distal atheromatous debris embolization, causes cerebrovascular events ...
Xiang-Dong Xiong   +3 more
doaj   +1 more source

Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study [PDF]

open access: yes, 2016
Background and Purpose Carotid artery atherosclerotic plaque composition may influence plaque stability and risk of thromboembolic events, and non-invasive plaque imaging may therefore permit risk stratification for clinical management.
Condon, B.   +7 more
core   +1 more source

Angiogenesis in the atherosclerotic plaque

open access: yesRedox Biology, 2017
Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries characterized by a local accumulation of cholesterol and non-resolving inflammation. Atherothrombotic complications are the leading cause of disability and mortality in western countries.
Anne Nègre-Salvayre   +4 more
openaire   +3 more sources

Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis [PDF]

open access: yes, 2017
Background and Purpose: Inflammation plays a key role in atherosclerosis. A protective role of angiotensin-(1-7) in vascular pathologies opened a possibility for therapeutic use of small molecule non-peptide Ang-(1-7) mimetics, such as AVE0991.
Czesnikiewicz-Guzik, M.   +11 more
core   +2 more sources

Noninvasive imaging of focal atherosclerotic lesions using fluorescence molecular tomography [PDF]

open access: yes, 2014
Insights into the etiology of stroke and myocardial infarction suggest that rupture of unstable atherosclerotic plaque is the precipitating event. Clinicians lack tools to detect lesion instability early enough to intervene, and are often left to manage ...
Abendschein, Dana R.   +9 more
core   +2 more sources

Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques

open access: yesFrontiers in Neurology, 2023
Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation.
Zhiwei He   +6 more
doaj   +1 more source

Npp1 promotes atherosclerosis in ApoE knockout mice. [PDF]

open access: yes, 2011
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PP(i)), a physiologic inhibitor of hydroxyapatite deposition.
Nitschke, Yvonne   +3 more
core   +1 more source

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