Results 51 to 60 of about 146,166 (354)
The role of p53 in atherosclerosis [PDF]
, 2006 Although the role of the tumour suppressor gene p53 is well known in cancer, recent studies have highlighted a fundamental role for p53 in regulating cells in the advanced atherosclerotic plaque, the major cause of heart attacks and stroke. In particular,
Bennett, M., Mercer, J.R.
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High-Resolution MRI of Intracranial Atherosclerotic Disease [PDF]
Neurointervention, 2014 Intracranial atherosclerotic disease (ICAD) causes up to 10% of all ischemic strokes, and the rate of recurrent vascular ischemic events is very high. Important predictors of vulnerability in atherosclerotic plaques include the degree of stenosis and the
Chang-Woo Ryu +3 more
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Progress in atherosclerotic plaque imaging
World Journal of Radiology, 2012 Cardiovascular diseases are the primary cause of mortality in the industrialized world, and arterial obstruction, triggered by rupture-prone atherosclerotic plaques, lead to myocardial infarction and cerebral stroke. Vulnerable plaques do not necessarily occur with flow-limiting stenosis, thus conventional luminographic assessment of the pathology ...
Soloperto Giulia, Casciaro Sergio
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Vulnerable Plaque, Characteristics, Detection, and Potential Therapies
Journal of Cardiovascular Development and Disease, 2019 Plaque development and rupture are hallmarks of atherosclerotic vascular disease. Despite current therapeutic developments, there is an unmet necessity in the prevention of atherosclerotic vascular disease. It remains a challenge to determine at an early
Anouar Hafiane
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Adiponectin and Vulnerable Atherosclerotic Plaques
Journal of the American College of Cardiology, 2011 High-risk plaques that are vulnerable to rupture demonstrate distinct morphological characteristics. They are differentiated from the lesions responsible for stable coronary artery disease by their large necrotic cores, thin-inflamed fibrous caps, and positive remodeling.
Dipika Gawande +2 more
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Mechanisms of erosion of atherosclerotic plaques [PDF]
Current Opinion in Lipidology, 2017 Purpose of review The present review explores the mechanisms of superficial intimal erosion, a common cause of thrombotic complications of atherosclerosis. Recent findings Human coronary artery atheroma that give rise to thrombosis because of erosion differ diametrically from those ...
Thibaut Quillard +4 more
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Advanced Science, 2021 Atherosclerotic plaque is the primary cause of cardiovascular disorders and remains a therapeutic hurdle for the early intervention of atherosclerosis. Traditional clinical strategies are often limited by surgery‐related complications or unsatisfactory ...
Yi Ma +6 more
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Femoral artery ultrasound examination: a new role in predicting cardiovascular risk [PDF]
, 2017 We compared intima-media thickness (IMT) and the prevalence of plaques in the common carotid artery (CCA) and common femoral artery (CFA) in apparently healthy participants. This multicenter study included 322 participants (59.9% female; age 20-78 years,
Baracchini, Claudio +14 more
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Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
, 2020 Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
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Calcifications in atherosclerotic plaques and impact on plaque biomechanics
Journal of Biomechanics, 2019 The catastrophic mechanical rupture of an atherosclerotic plaque is the underlying cause of the majority of cardiovascular events. The infestation of vascular calcification in the plaques creates a mechanically complex tissue composite. Local stress concentrations and plaque tissue strength properties are the governing parameters required to predict ...
Barrett, Hilary E. +4 more
openaire +3 more sources