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Phenotypic Shifts in Macrophages Within Advanced Atherosclerotic Plaques in Humans [PDF]

open access: yesFASEB BioAdvances
The importance of macrophage polarization through atherogenesis is established. However, most studies rely on immunohistological approaches, which have several limitations, such as precluding comprehensive phenotypic analysis.
Barbora Muffova   +11 more
doaj   +2 more sources

Neovascularization in Atherosclerotic Plaques: Clinical Implications, Detection, and Prevention Strategies [PDF]

open access: yesReviews in Cardiovascular Medicine
Following the global increase in atherosclerotic cardiovascular diseases, the demand for the effective identification of high-risk factors that lead to atherosclerotic plaque rupture and the search for new therapeutic targets has also increased ...
Long Zhang   +4 more
doaj   +2 more sources

Geometric consistency among atherosclerotic plaques in carotid arteries evaluated by multidimensional parameters [PDF]

open access: yesHeliyon
The three-dimensional (3D) geometry of carotid atherosclerotic plaques is associated with multiple cardiovascular diseases. However, it is unknown if carotid plaques of different sizes are consistent in 3D geometry, with a lack of quantitative ...
Ling Li   +6 more
doaj   +2 more sources

Follicle-stimulating hormone receptor expression in advanced atherosclerotic plaques [PDF]

open access: yesScientific Reports
Experimental evidence indicates that follicle-stimulating hormone (FSH), an essential hormone for reproduction, can act directly on endothelial cells inducing atherosclerosis activation and development.
Nicolae Ghinea   +4 more
doaj   +2 more sources

Blood microbiome of patients with atherosclerosis

open access: yesАтеросклероз, 2022
Aim of the study was to assess the composition of blood microbiome in patients with atherosclerosis, to compare it with microflora and microbiome of atherosclerotic plaques, to identify common taxons for microbiomes of blood and atherosclerotic plaques ...
Diliara M. Sharifullina   +2 more
doaj   +1 more source

Mass Spectrometry Imaging as a Tool to Investigate Region Specific Lipid Alterations in Symptomatic Human Carotid Atherosclerotic Plaques

open access: yesMetabolites, 2021
Atherosclerosis is characterized by fatty plaques in large and medium sized arteries. Their rupture can causes thrombi, occlusions of downstream vessels and adverse clinical events.
Francesco Greco   +6 more
doaj   +1 more source

The Influence of Calcification Factors and Endothelial-Dysfunction Factors on the Development of Unstable Atherosclerotic Plaques

open access: yesDiagnostics, 2020
Background: This study aimed to evaluate changes in markers of calcification and of endothelial dysfunction during the development of calcification and instability of atherosclerotic plaques and to identify associations of calcification factors with the ...
Yana V. Polonskaya   +8 more
doaj   +1 more source

Dendritic Cells Expressing Triggering Receptor Expressed on Myeloid Cells-1 Correlate with Plaque Stability in Symptomatic and Asymptomatic Patients with Carotid Stenosis. [PDF]

open access: yesPLoS ONE, 2016
Atherosclerosis is a chronic inflammatory disease with atherosclerotic plaques containing inflammatory cells, including T-lymphocytes, dendritic cells (DCs) and macrophages that are responsible for progression and destabilization of atherosclerotic ...
Vikrant Rai   +3 more
doaj   +1 more source

Genes involved in systemic and arterial bed dependent atherosclerosis--Tampere Vascular study. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Atherosclerosis is a complex disease with hundreds of genes influencing its progression. In addition, the phenotype of the disease varies significantly depending on the arterial bed.
Mari Levula   +20 more
doaj   +1 more source

Neutrophil extracellular traps and echogenicity of carotid atherosclerotic plaques

open access: yesФундаментальная и клиническая медицина, 2020
Aim. To study the association between the number of neutrophil extracellular traps (NETs) formed by circulating neutrophils and echogenicity of carotid atherosclerotic plaques. Materials and Methods.
I. I. Dolgushin   +7 more
doaj   +1 more source

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