The anticoagulant protein S (PS) binds phospholipids with very high affinity, but PS interaction with lipoproteins and lipidrich atherosclerotic plaques remains still poorly defined.
Marcello Baroni +8 more
doaj +1 more source
Angiogenesis in the atherosclerotic plaque
Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries characterized by a local accumulation of cholesterol and non-resolving inflammation. Atherothrombotic complications are the leading cause of disability and mortality in western countries.
Caroline Camaré +3 more
openaire +3 more sources
Travelling to Rome : inflammation, endoplasmic reticulum stress and angiogenesis during atherosclerotic plaque development [PDF]
Cardiovascular diseases are the leading cause of death worldwide followed by cancer. Atherosclerosis, the major underlying cause of cardiovascular diseases, is a syndrome affecting medium-sized and large arteries.
Kyriakakis, Emmanouil
core +1 more source
Stabilization of atherosclerotic plaques: an update [PDF]
The majority of coronary thrombi (∼75%) is caused by plaque rupture .1,2 Prototype of the rupture-prone plaque contains a large, soft, lipid-rich necrotic core with a thin and inflamed fibrous cap, so-called thin-cap fibroatheroma (TCFA) ( Figure 1 ).3,4 Other common features include expansive remodelling, large plaque size, plaque haemorrhage ...
Yla-Herttuala, S. +19 more
openaire +6 more sources
The biological effects of subacute inhalation of diesel exhaust following addition of cerium oxide nanoparticles in atherosclerosis-prone mice [PDF]
Background: Ceriumoxide(CeO2) nano particles improve the burning efficiency of fuel,however,little is known about health impacts of altered emissions from the vehicles.Methods: Atherosclerosis-prone apolipoprotein Eknockout (ApoE/) mice were exposed by ...
Boere, A. John F. +7 more
core +1 more source
Autophagy in Atherosclerosis: A Phenomenon Found in Human Carotid Atherosclerotic Plaques
Background: Autophagy has been found to be involved in animal and cell models of atherosclerosis, but to date, it lacks general observation in human atherosclerotic plaques. Here, we investigated autophagy in smooth muscle cells (SMCs), endothelial cells
Huihui Liu +6 more
doaj +1 more source
MULTI-DETECTOR CT CHARACTERIZATION OF CORONARY ATHEROMATOUS PLAQUES [PDF]
Background: Atherosclerotic cardiovascular diseases are the leading cause of death worldwide (30% of the mortalities).Coronary atherosclerotic plaques are classified into stable and unstable.
Ahmed Samy +4 more
doaj +1 more source
Vulnerable Atherosclerotic Plaque [PDF]
The recent proliferation of invasive and noninvasive techniques to locate vulnerable atherosclerotic plaques raises important questions. Will such techniques add useful prognostic information? If so, will the information prevent myocardial infarction, stroke, or death in at least some patients at risk? Will it lead to new research advances?
Ward, Casscells +2 more
openaire +2 more sources
Cathepsin Activity-Based Probes and Inhibitor for Preclinical Atherosclerosis Imaging and Macrophage Depletion. [PDF]
Cardiovascular disease is the leading cause of death worldwide, mainly due to an increasing prevalence of atherosclerosis characterized by inflammatory plaques.
Ihab Abd-Elrahman +8 more
doaj +1 more source
Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques. [PDF]
Activation of the transcription factor NF-κB appears to be involved in different stages of atherogenesis. In this paper we investigate the role of NF-κB inhibitor IκBα in atherosclerosis.
Menno P J de Winther +53 more
core +1 more source

