Results 11 to 20 of about 503,928 (378)

Autophagy in Atherosclerosis: A Phenomenon Found in Human Carotid Atherosclerotic Plaques

Chinese Medical Journal, 2015
Background: Autophagy has been found to be involved in animal and cell models of atherosclerosis, but to date, it lacks general observation in human atherosclerotic plaques. Here, we investigated autophagy in smooth muscle cells (SMCs), endothelial cells
Huihui Liu, Yongjun Cao, Tong Tong, Jijun Shi, Yanlin Zhang, Yaping Yang, Chunfeng Liu   +6 more
doaj   +2 more sources

Near-infrared autofluorescence induced by intraplaque hemorrhage and heme degradation as marker for high-risk atherosclerotic plaques

Nature Communications, 2017
Atherosclerosis diagnosis relies primarily on imaging and early detection of high-risk atherosclerotic plaques is important for risk stratification of patients and stabilization therapies. Here Htun et al.
Nay Min Htun, Yung Chih Chen, Bock Lim, Tara Schiller, Ghassan J. Maghzal, Alex L. Huang, Kirstin D. Elgass, Jennifer Rivera, Hans G. Schneider, Bayden R. Wood, Roland Stocker, Karlheinz Peter   +11 more
doaj   +2 more sources

Folate Receptor–Targeted Single-Photon Emission Computed Tomography/Computed Tomography to Detect Activated Macrophages in Atherosclerosis: Can It Distinguish Vulnerable from Stable Atherosclerotic Plaques?

Molecular Imaging, 2014
The need for noninvasive imaging to distinguish stable from vulnerable atherosclerotic plaques is evident. Activated macrophages play a role in atherosclerosis and express folate receptor folate receptor β (FR-β).
Leah C.J. Winkel, Harald C. Groen, Bibi S. van Thiel, Cristina Müller, Antonius F.W. van der Steen, Jolanda J. Wentzel, Marion de Jong, Kim Van der Heiden   +7 more
doaj   +2 more sources

Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning

Frontiers in Immunology, 2022
Objective The decreased stability of atherosclerotic plaques increases the risk of ischemic stroke. However, the specific characteristics of dysregulated immune cells and effective diagnostic biomarkers associated with stability in atherosclerotic ...
Jing Wang, Zijian Kang, Yandong Liu, Zifu Li, Yang Liu, Jianmin Liu   +5 more
semanticscholar   +1 more source

Platelet‐Mimicking Therapeutic System for Noninvasive Mitigation of the Progression of Atherosclerotic Plaques

Advancement of science, 2021
Atherosclerotic plaque is the primary cause of cardiovascular disorders and remains a therapeutic hurdle for the early intervention of atherosclerosis. Traditional clinical strategies are often limited by surgery‐related complications or unsatisfactory ...
Yi Ma, Yuxuan Ma, Mengqiu Gao, Zhihao Han, Wen Jiang, Yueqing Gu, Yi Liu   +6 more
semanticscholar   +1 more source

Ultraselective Carbon Nanotubes for Photoacoustic Imaging of Inflamed Atherosclerotic Plaques

Advanced Functional Materials, 2021
Disruption of vulnerable atherosclerotic plaques often leads to myocardial infarction and stroke, the leading causes of morbidity and mortality in the United States.
Mahsa Gifani, Devon J. Eddins, H. Kosuge, Yapei Zhang, Sesha L. A. Paluri, T. Larson, N. Leeper, L. Herzenberg, S. Gambhir, M. McConnell, E. Ghosn, B. Smith   +11 more
semanticscholar   +1 more source

Platelet Membrane-Coated Nanocarriers Targeting Plaques to Deliver Anti-CD47 Antibody for Atherosclerotic Therapy

Research, 2022
Atherosclerosis, the principle cause of cardiovascular disease (CVD) worldwide, is mainly characterized by the pathological accumulation of diseased vascular cells and apoptotic cellular debris.
Liang Chen, Zhong‐Liang Zhou, Chengxin Hu, M. Maitz, Li Yang, Rifang Luo, Yunbing Wang   +6 more
semanticscholar   +1 more source

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

Nature Communications, 2020
Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage
J. Baardman, S. Verberk, Saskia van der Velden, M. Gijbels, C. V. van Roomen, J. Sluimer, J. Broos, G. Griffith, K. Prange, M. van Weeghel, Soufyan Lakbir, D. Molenaar, E. Meinster, A. Neele, G. Kooij, H. D. de Vries, E. Lutgens, K. Wellen, M. D. de Winther, J. van den Bossche   +19 more
semanticscholar   +1 more source

ASSOCIATION OF MINERAL ELEMENTS IN THE ATHEROSCLEROTIC PLAQUE IN CORONARY ATHEROSCLEROSIS

Атеросклероз, 2019
Purpose: to determine the content of mineral elements in the homogenates of atherosclerotic plaques of human coronary arteries. Methods: research material – homogenates of samples of atherosclerotic plaques of coronary arteries obtained during ...
E. Ya. Zhuravskaya, T. I. Savchenko, O. V. Chankina, Ya. V. Polonskaya, E. V. Sadowski, E. M. Stakhneva, Yu. I. Ragino, A. M. Chernyavskii   +7 more
doaj   +1 more source

Association between serum visfatin levels and atherosclerotic plaque in patients with type 2 diabetes

Diabetology & Metabolic Syndrome, 2019
Background Visfatin is a multifaceted protein that plays an important role in regulating a variety of physiological and pathological processes, including obesity, diabetes and cardiovascular disease.
Long-Yi Zheng, Xia Xu, Ren-Hui Wan, Sheng Xia, Jin Lu, Qin Huang   +5 more
doaj   +1 more source