Results 201 to 210 of about 78,816 (306)

Transformative Advances in Vascular Surgery: Five Decades of Innovation in the Management of Aortic, Carotid, and Peripheral Arterial Disease

World Journal of Surgery, EarlyView.
Ghaleb A. Darwazeh, William Q. Duong, Ramola M. Panchal, Ahmed M. Abou‐Zamzam   +3 more
wiley   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source

Integrated single-cell atlas of human atherosclerotic plaques. [PDF]

Nat Commun
Traeuble K, Munz M, Pauli J, Sachs N, Vafadarnejad E, Carrillo-Roa T, Maegdefessel L, Kastner P, Heinig M.   +8 more
europepmc   +1 more source

Proteomic Profiling Captures Residual Cardiovascular Risk Beyond the PREVENT Model in Individuals With Cardiovascular–Kidney–Metabolic Syndrome Stages 2–3

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Cardiovascular–kidney–metabolic (CKM) syndrome reflects complex pathobiological interactions among metabolic disorders, kidney injury, and cardiovascular disease (CVD). Stages 2 and 3 represent critical phases of disease progression characterised by high pathological heterogeneity.
Xuefei Han, Jiacheng Ding, Jingqian Li, Yiyin Gao, Yunqian Li   +4 more
wiley   +1 more source

Insulin use promotes pro-inflammatory changes in the transcriptome of atherosclerotic plaques in patients with diabetes mellitus. [PDF]

J Mol Cell Cardiol Plus
Bradford A, Yoshida T, Sukhanov S, Woods FF, Delafontaine P, Bazan HA, Woods TC.   +6 more
europepmc   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

The FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki, Lydia‐Nefeli Thrapsanioti, Aikaterini Berdiaki, Ioanna Spyridaki, Dragana Nikitovic   +4 more
wiley   +1 more source

Targeted Sustained-Release Therapy for Vulnerable Atherosclerotic Plaques Using Luteolin-Loaded Nanoparticles. [PDF]

Int J Nanomedicine
Wang S, Shi X, Li X, Liu Y, Wang C, Wu Y, Wang Y, Qian W, Li X, Huang J, Li D, Xu T.   +11 more
europepmc   +1 more source

IgE And IgG Antibody Responses to α‐Gal and Association With Carotid Stenosis in Swedish Patients

Allergy, EarlyView.
Marija Perusko, Danijela Apostolovic, Jeanette Grundström, Malin Kronqvist, Mirjana Radomirovic, Anna Smed‐Sörensen, Ulf Hedin, Marianne van Hage   +7 more
wiley   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Integrated proteomics and metabolomics analyses reveal potential molecular signatures of rabbit atherosclerotic plaques. [PDF]

Int J Cardiol Heart Vasc
Zan C, Ji T, Zhang X, Yang MF, Wu Z, Li S.   +5 more
europepmc   +1 more source