Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
PCSK9 inhibitoRs for Early Passivation of coRonary athEroSclerotic plaqueS in acute coronary syndromes (REPRESS): study protocol for a multicentre randomised controlled trial. [PDF]
Chen Z +9 more
europepmc +1 more source
Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre +2 more
wiley +1 more source
Integration of Conventional and Radiomic Features From Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography/Magnetic Resonance Imaging for Multimodal Prediction of Symptomatic Carotid Atherosclerotic Plaques. [PDF]
Li Q +9 more
europepmc +1 more source
The Effect of Chlorhexidine Mouthwash on Blood Pressure: A Systematic Review and Meta‐Analysis
ABSTRACT Aim This study evaluated the effect of rinsing with a chlorhexidine containing mouthwash (CHX‐MW) on blood pressure (BP), as compared to rinsing with a control MW or no MW, based on (randomised) controlled trials and observational studies in humans. PROSPERO CRD42020222495.
Lars S. J. Toonen +5 more
wiley +1 more source
Low-intensity pulsed ultrasound responsive phase-change nanoparticles loaded with rapamycin for targeted therapy of atherosclerotic plaques. [PDF]
Wang D +9 more
europepmc +1 more source
ABSTRACT Aim To systematically review the evidence on the relationship between periodontal health interventions and the risk of first‐ever ischemic stroke. Materials and Methods Search strategy included electronic and hand searching to January 2025. MEDLINE (OVID), EMBASE (OVID), SCOPUS, LILACS, Web of Science (WOS) and Cochrane Central Register of ...
Jorge Moldes +7 more
wiley +1 more source
Single-Cell Transcriptomics of Human Pericarotid Lymph Nodes Indicating Stability of Carotid Atherosclerotic Plaques. [PDF]
Sun T +15 more
europepmc +1 more source
Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai +2 more
wiley +1 more source
Prevalence of Carotid Atherosclerotic Plaques and Stenosis in Adults with Familial Hypercholesterolemia Needs Reappraisal: Systematic Review and Meta-Analysis. [PDF]
Piechocki M +2 more
europepmc +1 more source

