Results 251 to 260 of about 503,928 (378)

64Cu-Labeled Divalent Cystine Knot Peptide for Imaging Carotid Atherosclerotic Plaques

Journal of Nuclear Medicine, 2015
Lei Jiang, Y. Tu, R. Kimura, F. Habte, Hao Chen, K. Cheng, Hongcheng Shi, S. Gambhir, Zhen Cheng   +8 more
semanticscholar   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Single-Cell Transcriptomics of Human Pericarotid Lymph Nodes Indicating Stability of Carotid Atherosclerotic Plaques. [PDF]

J Am Heart Assoc
Sun T, Wu Y, Liu G, Xue Z, Yu M, Mao B, Han M, Liang X, Ling L, You N, Ji L, Liu H, Xu C, Qin Z, Zhao P, Wang D.   +15 more
europepmc   +1 more source

Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic flux [PDF]

, 2018
Jeong, Se-Jin, Jung, In-hyuk
core   +1 more source

Glucocorticoid‐Induced TNFR‐Related Ligand as a Biomarker for Diagnosis and Severity of Asthma in Children

Pediatric Discovery, EarlyView.
Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li, Yan Li, Jinying Xiang, Yinying Ren, Mi Zhou, Fang Deng, Zhou Fu, Fengxia Ding   +7 more
wiley   +1 more source

Correction: Zhuriheng pills improve adipose tissue dysfunction and inflammation by modulating PPARγ to stabilize atherosclerotic plaques. [PDF]

Front Pharmacol
Zhai Q, Liang F, Yang G, Liu Z, Dong X, Bu R, Xue P, Na S, Zhang X, Zhao P, Wang X, Wei Q, Wang Y, Lu J.   +13 more
europepmc   +1 more source

Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype.

European Heart Journal, 2014
N. Hanssen, K. Wouters, M. Huijberts, M. Gijbels, J. Sluimer, J. Scheijen, S. Heeneman, E. Biessen, M. Daemen, M. Brownlee, D. D. de Kleijn, C. Stehouwer, G. Pasterkamp, C. Schalkwijk   +13 more
semanticscholar   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Platelets impair the resolution of inflammation in atherosclerotic plaques in insulin-resistant mice after lipid lowering. [PDF]

JCI Insight
Laskou M, Delbare S, Gildea M, Weinstock A, Moura Virginio V, La Forest M, Krautter F, Donahoe C, Amadori L, Eberhardt N, Barrett TJ, Giannarelli C, Berger JS, Fisher EA.   +13 more
europepmc   +1 more source

Identification of Clinically Distinct Clusters in Patients With Severe COPD Using Circulating Blood Cell Population Parameters

Respirology, EarlyView.
This study investigated whether blood cell population data, in addition to cell counts, can identify clinically relevant COPD subgroups. Four distinct inflammatory profiles were identified with distinct clinical characteristics. Cell population data have the potential to provide additional insights beyond inflammatory cell counts and improve patient ...
Pauline J. M. Kuks, Jorine E. Hartman, Else A. M. D. ter Haar, L. Joost van Pelt, Dirk‐Jan Slebos, Maarten van den Berge, Simon D. Pouwels   +6 more
wiley   +1 more source