Results 21 to 30 of about 503,928 (378)

The cell origins of foam cell and lipid metabolism regulated by mechanical stress in atherosclerosis

Frontiers in Physiology, 2023
Atherosclerosis is an inflammatory disease initiated by endothelial activation, in which lipoprotein, cholesterol, extracellular matrix, and various types of immune and non-immune cells are accumulated and formed into plaques on the arterial wall ...
Zhi Ouyang, Jian Zhong, Junyi Shen, Ye Zeng   +3 more
doaj   +1 more source

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]

, 2017
Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl, Ballabio, Andrea, Bhattacharya, Somashubhra, Crowley, Jan R, Dehestani, Babak, Diwan, Abhinav, Epelman, Slava, Evans, Trent D, Fan, Daping, Holloway, Karyn B, Javaheri, Ali, Micevych, Paul S, Razani, Babak, Schilling, Joel D, Sergin, Ismail, Song, Eric, Stokes, Carl J, Weihl, Conrad C, Zayed, Mohamed A, Zhang, Xiangyu   +19 more
core   +2 more sources

The Function, Regulation and Mechanism of Programmed Cell Death of Macrophages in Atherosclerosis

Frontiers in Cell and Developmental Biology, 2022
Atherosclerosis is a chronic progressive inflammatory vascular disease, which is an important pathological basis for inducing a variety of cardio-cerebrovascular diseases. As a kind of inflammatory cells, macrophages are the most abundant immune cells in
Chang Liu, Zecheng Jiang, Zhongjie Pan, Liang Yang   +3 more
doaj   +1 more source

The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis [PDF]

, 2011
Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial ...
Antunes, RF, Dumitriu, IE, Kaski, JC
core   +3 more sources

Atherosclerotic carotid plaque segmentation [PDF]

The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2005
Atherosclerosis is the major cause of heart attack and stroke in the western world. In this paper we present a computerized method for segmenting the athrerosclerotic carotid plaque from ultrasound images. The method uses the blood flow image first to detect the initial contour of the plaque, and then despeckle filtering and snakes to deform the ...
Loizou, Christos P., Pattichis, Constantinos S., Istepanian, Robert S H, Pantziaris, Marios, Nicolaides, Andrew N.   +4 more
openaire   +3 more sources

Research Progress on the Risk Factors and Outcomes of Human Carotid Atherosclerotic Plaques

Chinese Medical Journal, 2017
Objective: Atherosclerosis is an inflammatory process that results in complex lesions or plaques that protrude into the arterial lumen. Carotid atherosclerotic plaque rupture, with distal atheromatous debris embolization, causes cerebrovascular events ...
Xiang-Dong Xiong, Wei-Dong Xiong, Shang-Shen Xiong, Gui-Hai Chen   +3 more
doaj   +1 more source

Understanding the Clinical Implications of Intracranial Arterial Calcification Using Brain CT and Vessel Wall Imaging

Frontiers in Neurology, 2021
Background and Purpose: Intracranial arterial calcification (IAC) has been the focus of much attention by clinicians and researchers as an indicator of intracranial atherosclerosis, but correlations of IAC patterns (intimal or medial) with the presence ...
Wen-Jie Yang, Bruce A. Wasserman, Lu Zheng, Zhong-Qing Huang, Zhong-Qing Huang, Jia Li, Jill Abrigo, Simon Sin-man Wong, Michael Tin-cheung Ying, Winnie Chiu-Wing Chu, Lawrence Ka-sing Wong, Thomas Wai-Hong Leung, Xiang-Yan Chen   +12 more
doaj   +1 more source

Imaging atherosclerotic plaque inflammation [PDF]

Nature Clinical Practice Cardiovascular Medicine, 2008
Inflammation within atherosclerotic plaques is one of the main drivers of atherosclerotic plaque rupture, which frequently leads to clinical events such as myocardial infarction and stroke. Current gold standard techniques such as X-ray angiography and ultrasound can rapidly report on luminal encroachment but give no readout on inflammatory state of ...
James H F, Rudd, Zahi A, Fayad
openaire   +2 more sources

Relationship between subclasses low-density lipoprotein and carotid plaque

Translational Neuroscience, 2022
Low-density lipoprotein (LDL) cholesterol can lead to the occurrence of atherosclerotic plaques, but patients with normal LDL still have atherosclerotic plaques in clinical practice.
Pan Zhanhai, Guo Huiwen, Wang Qingqing, Tian Sha, Zhang Xiaoxuan, Li Chengbo, Ma Zheng   +6 more
doaj   +1 more source

Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque [PDF]

, 2018
Experimental studies showed that gut-derived lipopolysaccharide (LPS) is pro-atherogenic, however, its relationship with human atherosclerosis is still to be defined.
Cammisotto, Vittoria, Carnevale, Roberto, Frati, Giacomo, Irace, Luigi, Martinelli, Ombretta, Nocella, Cristina, Pacini, Luca, Pastori, Daniele, Petrozza, Vincenzo, Sciarretta, Sebastiano, Sorrentino, Veronica, Violi, Francesco   +11 more
core   +2 more sources