Results 121 to 130 of about 957,277 (312)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Territorio, familia y héroe: un análisis de textos escolares chilenos Território, família e herói: uma análise de livros didáticos do Chile Country, Family and Hero: An Analysis of Chilean Textbooks

open access: yesEducación y Educadores, 2011
En este artículo se exponen los resultados de una investigación enfocada a identificar el imaginario sobre ciudadanía en los textos de estudio de Historia y Geografía, durante la transición a la democracia en Chile.
Abelardo León-Donoso   +1 more
doaj  

Non-trivial Supersymmetry Correlations between ATLAS and CMS Observations

open access: yes, 2012
We present definite correlations between the CMS 5 \fb all-hadronic search employing the stransverse mass variable $M_{T2}$ and the ATLAS 5 \fb all-hadronic and multijet supersymmetry (SUSY) searches, suggesting the possibility that both the ATLAS and ...
Li, Tianjun   +3 more
core  

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Reflexión colectiva sistemática: un estudio orientado al desarrollo profesional docente

open access: yesPsicologia Escolar e Educacional
Resumen Este trabajo expone el curso seguido por una intervención para desarrollar reflexión colectiva sistemática, en reuniones de profesores de un establecimiento público de educación media de La Serena, Chile y las posibilidades de cambio a partir de ...
Jorge Catalán-Ahumada, Pablo J. Castro
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen   +5 more
wiley   +1 more source

A multi-method proposal to study the public space in the scale of neighborhood from a transactional approach [PDF]

open access: yes, 2012
La perspectiva transaccional resulta muy atractiva para analizar y actuar sobre el espacio público en la escala de barrio. Sin embargo, las diferencias metodológicas y de lenguaje entre las distintas disciplinas implicadas lo hacen bastante complejo.
Berroeta Torres, Hector Rodrigo   +1 more
core  

Introductie ATLAS-ti 6.2

open access: yes, 2012
Presentatie 13-03-2012. Kenniskring Rehabilitatie.
openaire  

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