Results 131 to 140 of about 3,054,495 (336)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

How Humans Change the Atmosphere [PDF]

open access: yes
This exercise is designed to introduce students to the idea that human activities can alter the chemistry or gaseous composition of the atmosphere, resulting in a variety of impacts on human health and the environment.
Chris Fox
core  

Overview of HLLV effluents in stratosphere and above [PDF]

open access: yes, 1980
The injection of large quantities of rocket exhaust effluent into the upper atmosphere by the heavy lift launch vehicle (HLLV) of the solar power satellite system is discussed. The exhaust products considered are CO, CO2, H2O, H2, and NO.
Brubaker, K. L.
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

The Atmosphere [PDF]

open access: yes
This exercise is intended to reinforce the importance of Earth's atmosphere to living organisms. Topics include our bodies' interactions with the atmosphere; its composition and structure; and natural changes in the atmosphere (weather).
Chris Fox
core  

Stellar atmospheres

open access: yes
This is a pre-print of a chapter for the Encyclopedia of Astrophysics (edited by I. Mandel, section editor F.R.N.
Puls, Joachim   +2 more
openaire   +2 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Spatial and Temporal Changes and Influencing Factors of Mercury in Urban Agglomeration Land Patterns: A Case from Changchun Area, Old Industrial Base of Northeast China

open access: yesLand
Mercury, a global pollutant with high biotoxicity, is widely distributed in soils, water bodies, and the atmosphere. Anthropogenic activities such as industrial emissions and coal combustion release large quantities of mercury into the environment ...
Zhe Zhang   +7 more
doaj   +1 more source

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