Results 51 to 60 of about 3,054,495 (336)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Remote Sensing, 2022 The results of modernization of a mobile lidar for the airborne monitoring of the methane content in the atmosphere are presented. The modernization was carried out on the basis of in situ tests, several engineering solutions, and preliminary numerical ...
Semyon V. Yakovlev +2 more
doaj +1 more source
, 1969 Telespectrograph for analyzing upper atmosphere by tracking bodies reentering atmosphere at high ...
Ameer, G. A., Walters, R. M.
core +1 more source
The Role of N2 as a Geo-Biosignature for the Detection and Characterization of Earth-like Habitats [PDF]
, 2019 Since the Archean, N2 has been a major atmospheric constituent in Earth's atmosphere. Nitrogen is an essential element in the building blocks of life, therefore the geobiological nitrogen cycle is a fundamental factor in the long term evolution of both ...
Cubillos, Patricio E. +6 more
core +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Temporal Evolution of the Size and Temperature of Betelgeuse's Extended Atmosphere
, 2015 We use the Very Large Array (VLA) in the A configuration with the Pie Town (PT) Very Long Baseline Array (VLBA) antenna to spatially resolve the extended atmosphere of Betelgeuse over multiple epochs at 0.7, 1.3, 2.0, 3.5, and 6.1 cm.
Brown, Alexander +6 more
core +1 more source
Ionization in atmospheres of brown dwarfs and extrasolar planets. IV. The effect of cosmic rays [PDF]
, 2013 Cosmic rays provide an important source for free electrons in Earth's atmosphere and also in dense interstellar regions where they produce a prevailing background ionization. We utilize a Monte Carlo cosmic ray transport model for particle energies of 10(
Helling, Christiane, Rimmer, Paul
core +2 more sources
Modelling dynamically driven global cloud formation microphysics in the HAT-P-1b atmosphere [PDF]
, 2023 Elspeth K. H. Lee
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source