Results 51 to 60 of about 97,786 (249)

Measurement report: Wintertime aerosol characterization at an urban traffic site in Helsinki, Finland [PDF]

Atmospheric Chemistry and Physics
Physical and chemical properties of particulate matter and concentrations of trace gases were measured at an urban site in Helsinki, Finland, for 5 weeks to investigate the effect of wintertime conditions on pollutants.
K. Teinilä, S. Saarikoski, H. Lintusaari, T. Lepistö, P. Marjanen, M. Aurela, H. Hellén, T. Tykkä, M. Lampimäki, J. Lampilahti, L. Barreira, T. Mäkelä, L. Kangas, J. Hatakka, S. Harni, J. Kuula, J. V. Niemi, H. Portin, J. Yli-Ojanperä, J. Yli-Ojanperä, V. Niemelä, M. Jäppi, K. Lehtipalo, K. Lehtipalo, J. Vanhanen, L. Pirjola, L. Pirjola, H. E. Manninen, T. Petäjä, T. Rönkkö, H. Timonen   +30 more
doaj   +1 more source

Soot Particle Agglomeration Inlet (SPAI) for Enabling Online Chemical Composition Measurement of Nanoparticles with the Aerosol Mass Spectrometer

Aerosol and Air Quality Research, 2021
Nanoparticles are a topic of interest because of their effects on human health and the climate, but the current options for evaluating their chemical composition—one of the key properties that determine the mechanisms of these effects—remain very limited
Sampsa Martikainen, Sanna Saarikoski, Paxton Juuti, Hilkka Timonen, Jorma Keskinen, Panu Karjalainen   +5 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Evaluation of the performance of a particle concentrator for online instrumentation [PDF]

Atmospheric Measurement Techniques, 2014
The performance of the miniature Versatile Aerosol Concentration Enrichment System (m-VACES; Geller et al., 2005) was investigated in laboratory and field studies using online instruments. Laboratory tests focused on the behavior of monodisperse ammonium
S. Saarikoski, S. Carbone, M. J. Cubison, R. Hillamo, P. Keronen, C. Sioutas, D. R. Worsnop, J. L. Jimenez   +7 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Development of a cavity-enhanced aerosol albedometer [PDF]

Atmospheric Measurement Techniques, 2014
We report on the development of a cavity-enhanced aerosol single-scattering albedometer based on incoherent broadband cavity-enhanced absorption spectroscopy (IBBCEAS) combined with an integrating sphere (IS) for simultaneous in situ measurements of ...
W. Zhao, X. Xu, M. Dong, W. Chen, X. Gu, C. Hu, Y. Huang, X. Gao, W. Huang, W. Zhang   +9 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mesoscale modeling study of the interactions between aerosols and PBL meteorology during a haze episode in Jing–Jin–Ji (China) and its nearby surrounding region – Part 1: Aerosol distributions and meteorological features [PDF]

Atmospheric Chemistry and Physics, 2015
The urbanized region ofJing(Beijing)-Jin(Tianjin)-Ji (alias of Hebei province) and its nearby surrounding region (3JNS) is becoming China's most polluted area by haze, exceeding even the Yangtze and Pearl river deltas.
H. Wang, M. Xue, X. Y. Zhang, H. L. Liu, C. H. Zhou, S. C. Tan, H. Z. Che, B. Chen, T. Li   +8 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source