Results 51 to 60 of about 3,876,387 (253)

Role of Tropical Cyclones in Determining ENSO Characteristics

Geophysical Research Letters, 2023
El Niño‐Southern Oscillation (ENSO) can effectively modulate global tropical cyclone (TC) activity, but the role TCs may play in determining ENSO characteristics remains unclear.
Hui Li, Aixue Hu, Gerald A. Meehl
doaj   +1 more source

Causes of variability in the summertime Antarctic boundary-layer climate [PDF]

, 2007
A high-resolution one-dimensional atmospheric model is used to assess the contribution of various surface characteristics and external forcings on the structure and dynamics of the atmospheric boundary layer (ABL) over the Antarctic Plateau in summer ...
van den Broeke, M.R., van As, D., Afd Marine and Atmospheric Research, Sub Dynamics Meteorology, Marine and Atmospheric Research   +4 more
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The Flexible Global Ocean‐Atmosphere‐Land System Model Grid‐Point Version 3 (FGOALS‐g3): Description and Evaluation

Journal of Advances in Modeling Earth Systems, 2020
This paper introduces the Flexible Global Ocean‐Atmosphere‐Land System Model: Grid‐Point Version 3 (FGOALS‐g3) and evaluates its basic performance based on some of its participation in the sixth phase of the Coupled Model Intercomparison Project (CMIP6 ...
Lijuan Li, Yongqiang Yu, Yanli Tang, Pengfei Lin, Jinbo Xie, Mirong Song, Li Dong, Tianjun Zhou, Li Liu, Lu Wang, Ye Pu, Xiaolong Chen, Lin Chen, Zhenghui Xie, Hongbo Liu, Lixia Zhang, Xin Huang, Tao Feng, Weipeng Zheng, Kun Xia, Hailong Liu, Jiping Liu, Yan Wang, Longhuan Wang, Binghao Jia, Feng Xie, Bin Wang, Shuwen Zhao, Zipeng Yu, Bowen Zhao, Jilin Wei   +30 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Modelling the dynamics and boundary processes of Svalbard glaciers [PDF]

, 2014
The focus of this thesis is on improving our understanding of surface and basal processes in the context of glaciers in Svalbard. At the surface, interactions with the atmosphere and underlying snow determine the surface mass balance.
van Pelt, W.J.J., Sub Dynamics Meteorology, Marine and Atmospheric Research   +2 more
core  

An idealized description for the diurnal cycle of the dry atmospheric boundary layer [PDF]

, 2019
We present a conceptual model for the diurnal cycle of the dry atmospheric boundary layer (ABL). It may serve as a framework for future numerical studies on the transitional dynamics that characterize the ABL over land. The conceptual model enables us to
Baas, Peter, van Hooft, J.A. (author), van de Wiel, B.J.H. (author), van de Wiel, B.J.H., van Tiggelen, Maurice (author), Ansorge, Cedrick (author), Wiel, Bas J.H. van de, Ansorge, Cedrick, Hooft, J. Antoon van, van Hooft, J.A., Baas, P., Baas, P. (author), van Tiggelen, Maurice   +12 more
core   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

North Pacific meltwater weakens the Atlantic Meridional Overturning Circulation and preconditions Heinrich Stadial 1

Nature Communications
Heinrich Stadials provide insights into a potential future weakening of the Atlantic Meridional Overturning Circulation (AMOC), yet the mechanisms driving AMOC weakening during these intervals remain elusive.
Chijun Sun, Jiang Zhu, Bette L. Otto-Bliesner, Esther C. Brady, Sophia I. Macarewich   +4 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source