Results 91 to 100 of about 4,122,931 (339)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Charge ratio of muons from atmospheric neutrinos

open access: yes, 2002
We calculate the intensities and angular distributions of positive and negative muons produced by atmospheric neutrinos. We comment on some sources of uncertainty in the charge ratio.
Agrawal   +13 more
core   +1 more source

Atmospheric new particle formation and growth: review of field observations

open access: yesEnvironmental Research Letters, 2018
This review focuses on the observed characteristics of atmospheric new particle formation (NPF) in different environments of the global troposphere. After a short introduction, we will present a theoretical background that discusses the methods used to ...
V. Kerminen   +5 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Development of four-dimensional atmospheric models (worldwide) [PDF]

open access: yes
Development of four dimensional atmospheric models from global data for predicting atmospheric attenuation encountered by earth resources observation ...
Greaves, J. R., Spiegler, D. B.
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Dust Properties and Radiative Impacts at a Suburban Site during 2004–2017 in the North China Plain

open access: yesRemote Sensing, 2019
Aerosols and their radiative effects are of primary interest in climate research because of their vital influence on climate change. Dust aerosols are an important aerosol type in the North China Plain (NCP), mainly as a result of long-range transport ...
Jinqiang Zhang   +5 more
doaj   +1 more source

The Atmospheric Pressure at the Surface of Mars [PDF]

open access: yes
Photoelectric observation of atmospheric pressure on Mars ...
Rakos, K. D.
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Accuracy Analysis of GNSS Water Vapor Inversion Based on PPP and Double-Difference Network in China Region

open access: yesGaoyuan qixiang
Using observation data from 945 ground-based Global Navigation Satellite System (GNSS) stations in the summer of 2023 in China, the double-difference (DD) network algorithm and Precise Point Positioning (PPP) algorithm were used to invert the ...
Jin LUO   +6 more
doaj   +1 more source

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