Results 71 to 80 of about 84,293 (267)
Charge Structure and Lightning Discharge in a Thunderstorm Over the Central Tibetan Plateau
Geophysical Research LettersThe evolution of charge structure involved in lightning discharge of a thunderstorm over the central Tibetan Plateau is investigated for the first time, based on the data from very high frequency interferometer, radar and sounding.
Dongxia Liu +10 more
doaj +1 more source
Deep Learning Model for Precipitation Nowcasting Based on Residual and Attention Mechanisms
Remote SensingNowcasting is a critical technology for disaster prevention and mitigation, and the accuracy of radar echo extrapolation directly impacts forecasting performance.
Zhan Zhang +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Earth and Planetary Physics, 2019 The unique geographical location and high altitude of the Tibetan Plateau can greatly influence regional weather and climate. In particular, the Asian summer monsoon (ASM) anticyclone circulation system over the Tibetan Plateau is recognized to be a ...
JinQiang Zhang +13 more
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Atmospheric Composition Observations [PDF]
, 2016 The composition of the atmosphere is a critical factor in understanding the nature and magnitude of processes associated with the planet’s energy balance, clouds and precipitation, biogeochemical cycling of nutrients, and public health and welfare. A detailed understanding of trace gases, aerosol particles, and hydrometeors is challenging due to the ...
openaire +3 more sources
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
A Novel Method for Estimating the Vertical Velocity of Air with a Descending Radiosonde System
Remote Sensing, 2019 Knowledge of vertical air motion in the atmosphere is important for both meteorological and climate studies due to its impact on clouds, precipitation and the vertical transport of air masses, heat, momentum, and composition.
Jinqiang Zhang +10 more
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source