Results 81 to 90 of about 4,122,931 (339)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Characteristics of Lake Chad Level Variability and Links to ENSO, Precipitation, and River Discharge
The Scientific World Journal, 2014 This study used trend, correlation, and wavelet analysis to characterize Lake Chad (LC) level fluctuations, river discharge, El Niño Southern Oscillation (ENSO), and precipitation regimes and their interrelationships.
Churchill Okonkwo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
LandLand-use change is an important cause of carbon emissions (CEs). In the context of achieving carbon peaking and carbon neutrality goals, understanding the coupling mechanisms between land-use change and CEs is of great significance for fostering regional
Wen Wang +4 more
doaj +1 more source
Evidence for oscillation of atmospheric neutrinos
, 1998 We present an analysis of atmospheric neutrino data from a 33.0 kiloton-year (535-day) exposure of the Super-Kamiokande detector. The data exhibit a zenith angle dependent deficit of muon neutrinos which is inconsistent with expectations based on ...
A. Habig +152 more
core +1 more source
The BErkeley Atmospheric CO 2 Observation Network: initial evaluation
, 2016 . With the majority of the world population residing in urban areas, attempts to monitor and mitigate greenhouse gas emissions must necessarily center on cities.
A. Shusterman +5 more
semanticscholar +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Upward negative leaders in positive triggered lightning: Stepping and branching in the initial stage
Geophysical Research Letters, 2017 By conducting comprehensive observation on the rarely triggered positive lightning flashes, two cases of upward negative leaders were quantitatively investigated with simultaneous data of current, optical, and electromagnetic field changes at fine time ...
Yunjiao Pu +6 more
doaj +1 more source
Air mass factor formulation for spectroscopic measurements from satellites: Application to formaldehyde retrievals from the Global Ozone Monitoring Experiment [PDF]
, 2001 . We present a new formulation for the air mass factor (AMF) to convert slant column measurements of optically thin atmospheric species from space into total vertical columns.
Arlene Fiore +35 more
core +3 more sources
Atmospheric new particle formation from sulfuric acid and amines in a Chinese megacity
Science, 2018 A puzzle of new particles Atmospheric particulates can be produced by emissions or form de novo. New particle formation usually occurs in relatively clean air.
L. Yao +29 more
semanticscholar +1 more source