Results 101 to 110 of about 4,999,272 (376)
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open Bio, EarlyView.We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
Atmospheric environment for Space Shuttle (STS-41G) launch [PDF]
Selected atmospheric conditions that were observed near Space Shuttle STS-41G launch time on October 5, 1984 at Kennedy Space Center in Florida are summarized.
Batts, G. W. +3 more
core +1 more source
A refraction study of the median ridge of the Kane fracture zone [PDF]
, 1987 Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric and Planetary Sciences, 1987.Bibliography: leaves 41-47.by George Micah Connor Blumberg.M ...
Blumberg, George Micah Connor
core
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
A Comparison Study of Indoor and Outdoor Air Quality in Nanjing, China
Aerosol and Air Quality Research, 2020 Because humans spend much of their time in indoor microenvironments, the air quality indoors has attracted significant attention. This study simultaneously conducted real-time indoor observations and comprehensive outdoor measurements of O3, CO and PM2.5
Ruochong Xu +9 more
doaj +1 more source
Nimbus-F to carry advanced weather instruments [PDF]
Meteorological research instruments launched aboard NASA's Nimbus-F spacecraft are briefly described along with the Nimbus satellite program initiated to develop an observatory system capable of meeting the research and development needs of the nation's ...
core +1 more source
FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Atmospheric environment for Space Shuttle (STS-51D) [PDF]
A summary of selected atmospheric conditions observed near the space shuttle STS-51D launch time on April 12, 1985, at Kennedy Space Center Florida is presented. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud),
Batts, G. W. +3 more
core +1 more source
Investigation of the relationship with infrasonic wave and auroral activity in the polar region [PDF]
, 2019 The Tenth Symposium on Polar Science/Ordinary sessions: [OS] Space and upper atmospheric sciences, Wed. 4 Dec.
Haruka Ohata
core +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
FEBS Open Bio, EarlyView.Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source