Results 81 to 90 of about 11,104,205 (309)
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
I. Paleomagnetism and crustal rotations along a shear zone, Las Vegas range, Southern Nevada ; II. Seismotectonics of the Tien Shan, Central Asia [PDF]
, 1988 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric, and Planetary Sciences, 1988.Includes bibliographies.by Michael Roy Nelson.Ph ...
Nelson, Michael Roy
core
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Geochemistry of Hawaiian dredged lavas [PDF]
, 1988 Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric and Planetary Sciences, 1988.Includes bibliographical references.by Philippe C.
Gurriet, Philippe C. (Philippe Charles)
core
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Momentum transport due to a squall line system over the tropical oceans [PDF]
, 1988 Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric and Planetary Sciences, 1988.Includes bibliographical references.by Chia-Yung Chang.M ...
Chang, Chia-Yung
core
International Journal of Aviation, Aeronautics, and Aerospace, 2015 Altimeter corrections for non-standard temperature pose a challenge because accurate calculations require detailed knowledge of the temperature structure of the atmosphere between the surface and the aircraft.
Thomas A Guinn, Frederick R. Mosher
doaj +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
Optical investigation of cometary nuclei [PDF]
, 1987 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept.
Meech, Karen Jean
core
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source