ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Comparing Unique Title Coverage of Web of Science and Scopus in Earth and Atmospheric Sciences.
The current journal titles in earth and atmospheric sciences, that are unique to each of two databases, Web of Science and Scopus, were identified using different methods.
Philip Barnett, Claudia Lascar
doaj +1 more source
The GLAS physical inversion method for analysis of HIRS2/MSU sounding data [PDF]
Goddard Laboratory for Atmospheric Sciences has developed a method to derive atmospheric temperature profiles, sea or land surface temperatures, sea ice extent and snow cover, and cloud heights and fractional cloud, from HIRS2/MSU radiance data.
Chahine, M. T. +3 more
core +1 more source
Yearly variations in Be-7 concentrations in surface air at Iceland and Japan for 15 years from 2003: Solar modulation of cosmogenic nuclide [PDF]
The Tenth Symposium on Polar Science/Ordinary sessions: [OS] Space and upper atmospheric sciences, Wed. 4 Dec.
Akira Kadokura +9 more
core +1 more source
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu +2 more
wiley +1 more source
Proceedings: Sixth Annual Workshop on Meteorological and Environmental Inputs to Aviation Systems [PDF]
The topics of interaction of the atmosphere with aviation systems, the better definition and implementation of services to operators, and the collection and interpretation of data for establishing operational criteria relating the total meteorological ...
Camp, D. W., Frost, W., Hershman, L. W.
core +1 more source
Inversion of Advective Volumetric Scatter with Atmospheric Radar and Cross-Radial Velocity Measurement [PDF]
The Tenth Symposium on Polar Science/Ordinary sessions: [OS] Space and upper atmospheric sciences, Wed. 4 Dec.
Koji Nishimura
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
A GCM simulation of the earth-atmosphere radiation balance for winter and summer [PDF]
The radiation balance of the earth-atmosphere system simulated by using the general circulation model (GCM) of the Laboratory for Atmospheric Sciences (GLAS) is examined in regards to its graphical distribution, zonally-averaged distribution, and global ...
Wu, M. L. C.
core +1 more source

