Results 71 to 80 of about 701,769 (305)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Nimbus-F to carry advanced weather instruments [PDF]

open access: yes
Meteorological research instruments launched aboard NASA's Nimbus-F spacecraft are briefly described along with the Nimbus satellite program initiated to develop an observatory system capable of meeting the research and development needs of the nation's ...

core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

A dataset of Beijing MST radar horizontal wind fields at Xianghe Station in 2012

open access: yes中国科学数据
The atmospheric horizontal wind is an essential parameter for studying atmospheric dynamic characteristics, processes, and dynamic coupling between the upper and lower atmosphere. MST (Mesosphere Stratosphere and Troposphere) radar plays a unique role in
Yufang Tian, Ze Chen, Daren Lyu
doaj   +1 more source

Numerical Model Derived Altimeter Correction Maps for Non-Standard Atmospheric Temperature and Pressure

open access: yesInternational Journal of Aviation, Aeronautics, and Aerospace, 2015
Altimeter corrections for non-standard temperature pose a challenge because accurate calculations require detailed knowledge of the temperature structure of the atmosphere between the surface and the aircraft.
Thomas A Guinn, Frederick R. Mosher
doaj   +1 more source

Atmospheric environment for Space Shuttle (STS-41G) launch [PDF]

open access: yes
Selected atmospheric conditions that were observed near Space Shuttle STS-41G launch time on October 5, 1984 at Kennedy Space Center in Florida are summarized.
Batts, G. W.   +3 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Atmospheric environment for Space Shuttle (STS-51D) [PDF]

open access: yes
A summary of selected atmospheric conditions observed near the space shuttle STS-51D launch time on April 12, 1985, at Kennedy Space Center Florida is presented. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud),
Batts, G. W.   +3 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Space Station medical sciences concepts [PDF]

open access: yes
Current life sciences concepts relating to Space Station are presented including the following: research, extravehicular activity, biobehavioral considerations, medical care, maintenance of dental health, maintaining health through physical conditioning ...
Johnson, P. C., Jr., Mason, J. A.
core   +1 more source

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