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Enhancing Quality Assurance using Virtual Design Engineering: Case Study of Space Shuttle Challenger

open access: yesInternational Journal of Aviation, Aeronautics, and Aerospace, 2015
Virtual Design Engineering is an emerging method of increasing quality of systems. Including Virtual Design as a part of the traditional established Failure Mode, Effects, and Criticality Analysis process greatly enhances hazard and risk analysis while ...
Kouroush Jenab, Scot Paterson
doaj   +1 more source

Atmospheric blockages as trigger of environmental contingencies in Mexico City

open access: yesHeliyon, 2019
Atmospheric pollution in cities is due to several human factors, for instance the number of cars in circulation, fuel efficiency and industrial waste, as well as orographic and meteorological conditions that determine air circulation. Ozone contingencies
Rafael Silva-Quiroz   +4 more
doaj   +1 more source

IAMAS: a century of international cooperation in atmospheric sciences [PDF]

open access: yesHistory of Geo- and Space Sciences, 2019
The International Association of Meteorology and Atmospheric Sciences (IAMAS) was founded in 1919 as the Section of Meteorology of the International Union of Geodesy and Geophysics (IUGG).
M. C. MacCracken, H. Volkert
doaj   +1 more source

Climate warming and summer monsoon breaks drive compound dry and hot extremes in India

open access: yesiScience, 2022
Summary: Considering the severe impacts of compound dry and hot extremes, we examine the primary drivers of CDHEs during the summer monsoon in India. Using ERA5 reanalysis, we show that most of the CDHEs in India occur during the droughts caused by the ...
Akshay Rajeev   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

An Industrial Internet-of-Things (IIoT) Open Architecture for Information and Decision Support Systems in Scientific Field Campaigns

open access: yesSensors
Information and decision support systems are essential to conducting scientific field campaigns in the atmospheric sciences. However, their development is costly and time-consuming since each field campaign has its own research goals, which result in ...
Yehuda Arav   +4 more
doaj   +1 more source

Positive feedback to regional climate enhances African wildfires

open access: yesiScience, 2023
Summary: Regional climate strongly regulates the occurrence of wildfires partly because drying of fuel load increases fires. The large amounts of aerosols released by wildfires can also strongly affect regional climate.
Aoxing Zhang, Yuhang Wang, Yufei Zou
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Origin of atmospheric aerosols at the Pierre Auger Observatory using backward trajectory of air masses

open access: yes, 2012
The Pierre Auger Observatory is the largest operating cosmic ray observatory ever built. Calorimetric measurements of extensive air showers induced by cosmic rays are performed with a fluorescence detector.
  +7 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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