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Enhancing Quality Assurance using Virtual Design Engineering: Case Study of Space Shuttle Challenger
Virtual Design Engineering is an emerging method of increasing quality of systems. Including Virtual Design as a part of the traditional established Failure Mode, Effects, and Criticality Analysis process greatly enhances hazard and risk analysis while ...
Kouroush Jenab, Scot Paterson
doaj +1 more source
Atmospheric blockages as trigger of environmental contingencies in Mexico City
Atmospheric pollution in cities is due to several human factors, for instance the number of cars in circulation, fuel efficiency and industrial waste, as well as orographic and meteorological conditions that determine air circulation. Ozone contingencies
Rafael Silva-Quiroz +4 more
doaj +1 more source
IAMAS: a century of international cooperation in atmospheric sciences [PDF]
The International Association of Meteorology and Atmospheric Sciences (IAMAS) was founded in 1919 as the Section of Meteorology of the International Union of Geodesy and Geophysics (IUGG).
M. C. MacCracken, H. Volkert
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Climate warming and summer monsoon breaks drive compound dry and hot extremes in India
Summary: Considering the severe impacts of compound dry and hot extremes, we examine the primary drivers of CDHEs during the summer monsoon in India. Using ERA5 reanalysis, we show that most of the CDHEs in India occur during the droughts caused by the ...
Akshay Rajeev +2 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Information and decision support systems are essential to conducting scientific field campaigns in the atmospheric sciences. However, their development is costly and time-consuming since each field campaign has its own research goals, which result in ...
Yehuda Arav +4 more
doaj +1 more source
Positive feedback to regional climate enhances African wildfires
Summary: Regional climate strongly regulates the occurrence of wildfires partly because drying of fuel load increases fires. The large amounts of aerosols released by wildfires can also strongly affect regional climate.
Aoxing Zhang, Yuhang Wang, Yufei Zou
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Pierre Auger Observatory is the largest operating cosmic ray observatory ever built. Calorimetric measurements of extensive air showers induced by cosmic rays are performed with a fluorescence detector.
+7 more
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

