Results 41 to 50 of about 11,104,205 (309)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

University of Arizona, Institute of Atmospheric Physics, Progress Report No. 4

, 1957
This title from the Institute of Atmospheric Physics Reports collection is made available by the Department of Hydrology & Atmospheric Sciences and the University Libraries, University of Arizona.
Kassander, A. Richard, Jr.
core   +1 more source

Bibliografía sobre organismos, ambientes y procesos marinos y atmosféricos en Bahía Culebra, Pacífico norte, Guanacaste, Costa Rica (1922-2012) Bibliography on marine organisms, environments, and oceanographic and atmospheric processes in Bahía Culebra, north Pacific, Costa Rica (1922-2012)

Revista de Biología Tropical, 2012
Bahía Culebra se locoaliza en la parte norte de la costa Pacífica de Costa Rica. Es una región de afloramiento estacional, rica en ambientes y organismos marinos, y además, la zona de mayor desarrollo turístico del país. En este trabajo compilo y analizo
Jorge Cortés
doaj  

Increased confidence in satellite-derived cloud-evolution properties from combined track-and-type analysis

Meteorologische Zeitschrift
Automated object-based cloud-tracking algorithms allow for processing large amounts of time-resolved satellite observations for studying cloud evolution.
Felix Müller, Torsten Seelig, Matthias Tesche   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

University of Arizona, Institute of Atmospheric Physics, Progress Report No. 1

, 1954
This title from the Institute of Atmospheric Physics Reports collection is made available by the Department of Hydrology & Atmospheric Sciences and the University Libraries, University of Arizona.
Braham, Roscoe R., Jr.
core   +1 more source

The Impact of Thunderstorms on Take-off Data in South Africa

International Journal of Aviation, Aeronautics, and Aerospace
Aviation and meteorology are entwined disciplines, as aviation occurs in the atmosphere. Prevailing weather conditions at take-off are of utmost importance to aviation. This determines the payload of the aircraft and runway in use.
Quinton Jacobs
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

On Atmospheric Lapse Rates

International Journal of Aviation, Aeronautics, and Aerospace, 2019
We have derived and summarized and most important atmospheric temperature lapse rates. ALRs essentially govern vertical atmospheric air stability and creation of some cloud types.
Nihad E Daidzic
doaj   +1 more source

Atmospheric science: Cloudy, with a chance of science [PDF]

Nature, 2009
When American and Chinese scientists agreed to measure pollution and dust over China, nobody foresaw how difficult it would be. Jane Qiu reports.
openaire   +1 more source