Results 41 to 50 of about 11,992,322 (279)

Inverse modeling of European CH4 emissions: sensitivity to the observational network [PDF]

open access: yes, 2009
Inverse modeling is widely employed to provide “top-down” emission estimates using atmospheric measurements. Here, we analyze the dependence of derived CH4 emissions on the sampling frequency and density of the observational surface network, using the ...
Bergamaschi, P.   +9 more
core   +2 more sources

Characteristics of Updrafts in Thunderstorms

open access: yes, 1978
UA-IAP-SR-78-31Research supported by the Atmospheric Sciences Section, National Science Foundation, NSF Grants ATM73-06558A03 and ATM78-10082This title from the Institute of Atmospheric Physics Reports collection is made available by the Department of ...
Battan, Louis J.
core   +5 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Extreme heat exacerbates atmospheric ozone pollution: Holistic data-based causal investigation in China

open access: yesiScience
Summary: Climate change-induced extreme heat (EH) events intensify atmospheric surface ozone (O3) pollution, posing growing threats to public health and environment. To address the lack of rigorous empirical confirmation regarding the causal impact of EH
Ruixun Xia   +7 more
doaj   +1 more source

Climate warming and summer monsoon breaks drive compound dry and hot extremes in India

open access: yesiScience, 2022
Summary: Considering the severe impacts of compound dry and hot extremes, we examine the primary drivers of CDHEs during the summer monsoon in India. Using ERA5 reanalysis, we show that most of the CDHEs in India occur during the droughts caused by the ...
Akshay Rajeev   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Society needs experts with climate change competencies – what is the role of higher education in atmospheric and Earth system sciences?

open access: yesTellus: Series B, Chemical and Physical Meteorology, 2021
The urgent societal need for climate action requires climate change expertise. But who is a climate change expert? What is the role of atmospheric and Earth system science education?
Laura Riuttanen   +3 more
doaj   +1 more source

Positive feedback to regional climate enhances African wildfires

open access: yesiScience, 2023
Summary: Regional climate strongly regulates the occurrence of wildfires partly because drying of fuel load increases fires. The large amounts of aerosols released by wildfires can also strongly affect regional climate.
Aoxing Zhang, Yuhang Wang, Yufei Zou
doaj   +1 more source

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