Results 41 to 50 of about 223,618 (266)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The Impact of Thunderstorms on Take-off Data in South Africa

International Journal of Aviation, Aeronautics, and Aerospace
Aviation and meteorology are entwined disciplines, as aviation occurs in the atmosphere. Prevailing weather conditions at take-off are of utmost importance to aviation. This determines the payload of the aircraft and runway in use.
Quinton Jacobs
doaj   +1 more source

On Atmospheric Lapse Rates

International Journal of Aviation, Aeronautics, and Aerospace, 2019
We have derived and summarized and most important atmospheric temperature lapse rates. ALRs essentially govern vertical atmospheric air stability and creation of some cloud types.
Nihad E Daidzic
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Bibliografía sobre organismos, ambientes y procesos marinos y atmosféricos en Bahía Culebra, Pacífico norte, Guanacaste, Costa Rica (1922-2012) Bibliography on marine organisms, environments, and oceanographic and atmospheric processes in Bahía Culebra, north Pacific, Costa Rica (1922-2012)

Revista de Biología Tropical, 2012
Bahía Culebra se locoaliza en la parte norte de la costa Pacífica de Costa Rica. Es una región de afloramiento estacional, rica en ambientes y organismos marinos, y además, la zona de mayor desarrollo turístico del país. En este trabajo compilo y analizo
Jorge Cortés
doaj  

Atmospheric levels of BPA associated with particulate matter in an urban environment

Heliyon, 2019
Bisphenol A (BPA) is an Endocrine disruptor compound (EDC), capable of interfering with hormone related pathways and cause adverse effects, for example, in the reproductive system in wildlife and humans.
Natalia Soledad Graziani, Hebe Carreras, Eduardo Wannaz   +2 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Large-scale circulation shapes the spatial organization of anomalous precipitation over Northern Jiangsu

iScience
Summary: Anomalous precipitation events often exhibit coherent spatial organization rather than isolated intensity extremes, reshaping regional flood risk in subtropical monsoon zones.
Ying Xu, Hongyuan Fang, Wenpeng Zhao, Jian Zhang, Shuping Ma, Chuanqiao Zhou, Mingrui Shi   +6 more
doaj   +1 more source

Society needs experts with climate change competencies – what is the role of higher education in atmospheric and Earth system sciences?

Tellus: Series B, Chemical and Physical Meteorology, 2021
The urgent societal need for climate action requires climate change expertise. But who is a climate change expert? What is the role of atmospheric and Earth system science education?
Laura Riuttanen, Taina Ruuskanen, Mikko Äijälä, Anniina Lauri   +3 more
doaj   +1 more source

Analysis of Droughts in the Central Region of South Africa and Their Association with SST Anomalies [PDF]

, 2014
Published ArticleThe objective of this study was to characterise meteorological droughts in the Central Region of South Africa using Standardised Precipitation Evapotranspiration Index (SPEI) and to examine if there is a relationship between drought and
Welderufael, Worku A., Woyessa, Yali E., Edossa, Desalegn C.   +2 more
core