Results 81 to 90 of about 5,060,183 (339)

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source

An 11-year global gridded aerosol optical thickness reanalysis (v1.0) for atmospheric and climate sciences

, 2016
. While stand alone satellite and model aerosol products see wide utilization, there is a significant need in numerous atmospheric and climate applications for a fused product on a regular grid.
P. Lynch, J. Reid, D. Westphal, Jianglong Zhang, Timothy F. Hogan, E. Hyer, C. Curtis, D. Hegg, Y. Shi, James R. Campbell, J. Rubin, W. Sessions, F. J. Turk, A. Walker   +13 more
semanticscholar   +1 more source

Land–atmosphere feedbacks exacerbate concurrent soil drought and atmospheric aridity

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Soil drought and atmospheric aridity can be disastrous for ecosystems and society. This study demonstrates the critical role of land–atmosphere feedbacks in driving cooccurring soil drought and atmospheric aridity.
Sha Zhou, Sha Zhou, A. P. Williams, A. Berg, B. Cook, B. Cook, Yao Zhang, S. Hagemann, R. Lorenz, S. Seneviratne, P. Gentine   +10 more
semanticscholar   +1 more source

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

FEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang, Jiang Tan, Xueting He, Yuqin Chen, Guoping Qiu, Mei Yang   +5 more
wiley   +1 more source

Frequency of the winter temperature extremes over Siberia dominated by the Atlantic Meridional Overturning Circulation

npj Climate and Atmospheric Science, 2022
Widespread observed and projected increases in warm extremes, along with decreases in cold extremes, have been confirmed as being consistent with global and regional warming.
Huan Wang, Zhiyan Zuo, Liang Qiao, Kaiwen Zhang, Cheng Sun, Dong Xiao, Zouxing Lin, Lulei Bu, Ruonan Zhang   +8 more
doaj   +1 more source

Constraints on the Size and Composition of the Ancient Martian Atmosphere from Coupled CO2-N2-Ar Isotopic Evolution Models [PDF]

arXiv, 2023
Present-day Mars is cold and dry, but mineralogical and morphological evidence shows that liquid-water existed on the surface of ancient Mars. In order to explain this evidence and assess ancient Mars's habitability, one must understand the size and composition of the ancient atmosphere.
arxiv  

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Preface: 6th International Electronic Conference on Atmospheric Sciences

Environmental Sciences Proceedings
The sixth International Electronic Conference on Atmospheric Sciences, the range of topics will remain more general, but we are open to subject areas with a thematic topic of importance, especially interdisciplinary or transdisciplinary science [...]
Anthony R. Lupo
doaj   +1 more source

Grand challenges in atmospheric science [PDF]

Frontiers in Earth Science, 2013
As a subject of study, the atmospheric sciences encompass all the processes that occur in the atmosphere, together with its links with other systems, mainly the hydrosphere, cryosphere, lithosphere, biosphere, and outer space. As such it is an extensive discipline and the task of describing the main challenges is not an easy one, and entails a fair ...
openaire   +2 more sources

Origin of Life Molecules in the Atmosphere After Big Impacts on the Early Earth [PDF]

arXiv, 2023
The origin of life on Earth would benefit from a prebiotic atmosphere that produced nitriles, like HCN, which enable ribonucleotide synthesis. However, geochemical evidence suggests that Hadean air was relatively oxidizing with negligible photochemical production of prebiotic molecules.
arxiv